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Cat. No.: HY-123605

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CAY10406

CAY10406 is an inhibitor for caspase 3/7. CAY10406 inhibits the expression of 28-kDa IL-1β fragment, without significant cytotoxicity (10 μM).

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CAS No.: 2108603-03-6
Formule: C₂₇H₂₃F₃N₂O₅S
Masse moléculaire:544.54

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

CAY10406 Chemical Structure

CAS No.: 2108603-03-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

CAY10406 is an inhibitor for caspase 3/7. CAY10406 inhibits the expression of 28-kDa IL-1β fragment, without significant cytotoxicity (10 μM)^[1].

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Chemical Information

CAS No. 2108603-03-6
Masse moléculaire 544.54
Formule C₂₇H₂₃F₃N₂O₅S
SMILES

O=S(C1=CC=C(C(C(C2=O)=O)=C1)N2CC3=CC=CC=C3)(N4[C@@H](CCC4)COC5=CC=C(C=C5)C(F)(F)F)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Pathak S, et al., Autoimmune inner ear disease patient-associated 28-kDa proinflammatory IL-1β fragment results from caspase-7-mediated cleavage in vitro. JCI Insight. 2020 Feb 13;5(3):e130845. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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CAY10406

Z-Phe-Tyr(tBu)-diazomethylketone

Fluostatin B

Z-AEVD-FMK

Ac-LEHD-AMC

Fluostatin A sodium

Z-IETD-AFC

Boc-Glu-OBzl

Ac-LETD-AFC

Ac-DNLD-AMC

Voir tous les produits spécifiques à Isoform Caspase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CAY10406

Z-Phe-Tyr(tBu)-diazomethylketone

Fluostatin B

Z-AEVD-FMK

Ac-LEHD-AMC

Fluostatin A sodium

Z-IETD-AFC

Boc-Glu-OBzl

Ac-LETD-AFC

Ac-DNLD-AMC

Voir tous les produits spécifiques à Isoform Caspase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CAY10406 Related Classifications

HY-123605 Related Classifications