pro-FTY
pro-FTY, a FTY720 (HY-12005) anticancer prodrug, is a sphingosine-1-phosphate (S1P) (HY-108496) inhibitor. pro-FTY specifically inhibits S1P signaling in cancer cells using a drug delivery system (DDS) that reacts with acrolein. pro-FTY significantly inhibits the survival of breast cancer cells, including multidrug-resistant cells and its organoids resistant to Paclitaxel (HY-B0015) or Doxorubicin (HY-15142A). pro-FTY potently suppresses tumor growth in 4T1 cells or organoids xenograft tumors mice model while avoiding lymphocytopenia.
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- CAS No.: 3064707-13-4
- Formule: C33H50N4O4
- Masse moléculaire:566.77
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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p-STAT3 |
Chemical Information
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CAS No. 3064707-13-4
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Masse moléculaire 566.77
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Formule C33H50N4O4
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SMILES
OCC(NC(OCC1=CC(C(C)C)=C(N=[N+]=[N-])C(C(C)C)=C1)=O)(CO)CCC2=CC=C(CCCCCCCC)C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
pro-FTY Related Classifications
HY-175201 Related Classifications
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