UPF-1035
UPF-1035 is a selective PARP-2 inhibitor with an IC50 value of 0.15 μM. UPF-1035 increases CA1 pyramidal cell loss in hippocampal and has neuroprotective activity.
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- CAS No.: 370872-09-6
- Formule: C16H11NO3
- Masse moléculaire:265.26
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
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PARP-1 9 μM (IC50) |
PARP-2 0.15 μM (IC50) |
Chemical Information
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CAS No. 370872-09-6
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Masse moléculaire 265.26
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Formule C16H11NO3
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SMILES
O=C1C2=CC=CC(OC(C3=CC=CC=C3)=O)=C2C=CN1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)