Cinitapride monotartrate
Cinitapride monotartrate is a 5-HT1A and 5-HT4 agonist. Cinitapride monotartrate is also a 5-HT2A and D2 antagonist. Cinitapride monotartrate can be used for the research of functional dyspepsia.
For research use only. We do not sell to patients.
- CAS No.: 1207859-16-2
- Formula: C25H36N4O10
- Molecular Weight:552.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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5-HT1A Receptor |
5-HT2A Receptor |
5-HT2 Receptor |
5-HT1 Receptor |
5-HT4 Receptor |
D2 Receptor |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wistar rats with gastric ulceration[2]
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Dosage:0.25-1 mg/kg
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Administration:Intraperitoneal injection; 0.25-1 mg/kg; once
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Result:Reduced haemorrhagic lesions compared with the ulcerated control group.
Decreased the percentage of ulceration to 28.76% at the highest dose (1 mg/kg).
Attenuated the increase myeloperoxidase activity (p<0.05, p<0.01).
Increased GSH-px activity in the gastric mucosa.
Chemical Information
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CAS No. 1207859-16-2
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Molecular Weight 552.57
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Formula C25H36N4O10
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SMILES
O=C(NC1CCN(CC2CC=CCC2)CC1)C3=CC([N+]([O-])=O)=C(N)C=C3OCC.O=C(O)[C@H](O)[C@@H](O)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Du Y, et al. Efficacy and safety of cinitapride in the treatment of mild to moderate postprandial distress syndrome-predominant functional dyspepsia. J Clin Gastroenterol. 2014 Apr;48(4):328-35. [Content Brief]
[2]. Alarcón de la Lastra C, et al. Effects of cinitapride on gastric ulceration and secretion in rats. Inflamm Res. 1998 Mar;47(3):131-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cinitapride monotartrate Related Classifications
HY-128386 Related Classifications
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