1. Cell Cycle/DNA Damage
  2. Aurora Kinase
  3. dAURK-4


Cat. No.: HY-137344
Handling Instructions

dAURK-4, an Alisertib derivative, is a potent and selective AURKA (Aurora A) degrader. dAURK-4 has anticancer effects.

For research use only. We do not sell to patients.

dAURK-4 Chemical Structure

dAURK-4 Chemical Structure

CAS No. : 2705844-81-9

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dAURK-4, an Alisertib derivative, is a potent and selective AURKA (Aurora A) degrader. dAURK-4 has anticancer effects[1].

IC50 & Target[1]

Aurora A


In Vitro

dAURK-4 (125-1000 nM; 4-24 hours) shows degradation of AURKA in a dose-depended manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: MM.1S cells
Concentration: 125 nM, 250 nM, 500 nM, 1000 nM
Incubation Time: 4 hours or 24 hours
Result: Inhibited the protein level of AURKA (Aurora A).
Molecular Weight





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