PUC-10
PUC-10 is a 5-HT6 receptor antagonist with a Ki of 14.6 nM and an IC50 of 32 nM. In silico predictions suggest that PUC-10 is orally active and can cross the blood-brain barrier. PUC-10 can induce autophagy in SH-SY5Y cells by inhibiting the mTOR pathway. PUC-10 can be used in the research of neurological disorders.
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- CAS. Nr.: 2064126-76-5
- Formel: C31H31N3O4S
- Molecular Weight:541.66
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
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5-HT6 Receptor |
Chemical Information
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CAS. Nr. 2064126-76-5
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Molecular Weight 541.66
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Formel C31H31N3O4S
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SMILES
OC(C1=CN(S(=O)(C2=C3C=CC=CC3=CC=C2)=O)C4=C1C=CC=C4)CN5CCN(C6=CC=CC=C6OC)CC5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)