DDO-8958
DDO-8958 is an orally active and selective BET BD1 inhibitor with a KD of 5.6 nM for BRD4 BD1. DDO-8958 exhibits low nanomolar inhibitory activity against all BET BD1 bromodomains except for BRDT BD1. DDO-8958 can inhibit the proliferation and migration, induce apoptosis and cell cycle arrest of tumor cells. DDO-8958 has anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 3017180-18-3
- Formula: C22H22FN5O2
- Molecular Weight:407.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 3017180-18-3
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Molecular Weight 407.44
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Formula C22H22FN5O2
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SMILES
FC1=C(C=C(C=C1C2=C3NC=NC3=NC=C2)OCC4COC4)C5=C(N(N=C5C)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)