EPZ030456
EPZ030456 is a potent and selective SMYD3 inhibitor with an IC50 of 48 nM. EPZ030456 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1808011-23-5
- Formula: C28H34ClN5O4S
- Molecular Weight:572.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Histone Methyltransferase Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
48 nM
Compound: EPZ030456
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Inhibition of human SMYD3 expressed in HEK293T/17 cells using FLAG-tagged MEKK2 as substrate incubated for 30 mins in low air flow area followed by incubation for 24 hrs at 37 degC by Western blot analysis
Inhibition of human SMYD3 expressed in HEK293T/17 cells using FLAG-tagged MEKK2 as substrate incubated for 30 mins in low air flow area followed by incubation for 24 hrs at 37 degC by Western blot analysis
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[PMID: 26985287] |
Chemical Information
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CAS No. 1808011-23-5
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Molecular Weight 572.12
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Formula C28H34ClN5O4S
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SMILES
O=S(N1[C@]2([H])C[C@H](C[C@@]1([H])CC2)NC(C3=C(Cl)C=C(NC(C4)=O)C4=C3)=O)(N5CCC(CC5)NCC6=CC=CC=C6)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EPZ030456 Related Classifications
HY-122223 Related Classifications
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