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Cat. No.: HY-117614

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WF-210

WF-210 is a potent procaspase-3 activator with an EC₅₀ value of 0.95 μM. WF-210 induces Apoptosis. WF-210 has anti-tumor activity.

For research use only. We do not sell to patients.

CAS No.: 1242279-00-0
Formula: C₄₁H₃₈FN₇O₇S
Molecular Weight:791.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

WF-210 Chemical Structure

CAS No.: 1242279-00-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

WF-210 is a potent procaspase-3 activator with an EC₅₀ value of 0.95 μM. WF-210 induces Apoptosis. WF-210 has anti-tumor activity^[1].

IC₅₀ & Target

Procaspase-3

0.95 μM (IC₅₀)

All Caspase Isoforms :

Chemical Information

CAS No. 1242279-00-0
Molecular Weight 791.85
Formula C₄₁H₃₈FN₇O₇S
SMILES

O=C(CN1CCN(CC1)CC2=NC(C3=CC=C(COC4=CC=C(C=C4)F)C=C3)=NO2)N/N=C/C5=CC=C(C=C5O)OCC6=CSC(CC7=CC=C8OCOC8=C7)=N6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang F, et al. A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts. Mol Oncol. 2014 Dec;8(8):1640-52. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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WF-210

All Caspase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

WF-210 Related Classifications

HY-117614 Related Classifications