Dot1L-IN-8
Dot1L-IN-8 (Compound 15) is a potent Dot1L inhibitor. Dot1L-IN-8 inhibits HL-60, K562, MV4-11, HH, and KG-1 cells vitality with IC50s of 0.45, 1.03, 0.68, 1.66, and 1.12 μM, respectively.
For research use only. We do not sell to patients.
- Formula: C41H53N7O3S
- Molecular Weight:723.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 723.97
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Formula C41H53N7O3S
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SMILES
NC1=C2N=CN(C2=NC=N1)[C@@H]3O[C@H](CN4CCC(CNCC5=CC(C6=CC=C(C(C)(C)C)C=C6)=C(C7=CC=C(C(C)(C)C)C=C7)S5)CC4)[C@@H](O)[C@H]3O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)