ED11
ED11 is a potent and selective caspase-6 inhibitor with an IC50 of 12.12 nM. ED11 competes with Htt for the caspase-6 active site, and thus reduce Htt cleavage. ED11 can cross the blood-brain barrier (BBB). ED11 has the potential for the study of Huntington's disease (HD).
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- No. CAS: 1593480-56-8
- Fòrmula: C116H205N47O37
- Peso molecular:2850.16
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 1593480-56-8
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Peso molecular 2850.16
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Fòrmula C116H205N47O37
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Sequence
Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln-Ser-Ser-Glu-Ile-Val-Leu-Asp-Gly-Thr-Asp-Asn
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Sequence Shortening
GRKKRRQRRRPPQSSEIVLDGTDN
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ED11 Related Classifications
HY-P10822 Related Classifications
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