MT-21
MT-21 is an Apoptosis inducer and adenine nucleotide translocase inhibitor. MT-21 induces Apoptosis by activating JNK via the Krs/MST protein. MT-21 activates caspase-3 via caspase-9. MT-21 induces the release of cytochrome c. MT-21 can be used in the research of tumors.
For research use only. We do not sell to patients.
- CAS No.: 186379-49-7
- Formula: C16H27NO3
- Molecular Weight:281.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 186379-49-7
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Molecular Weight 281.39
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Formula C16H27NO3
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SMILES
O=C1N(CCCCCCCC)C(C)(O)C(C)=C1C(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Watabe M, Machida K, Osada H. MT-21 is a synthetic apoptosis inducer that directly induces cytochrome c release from mitochondria. Cancer Res. 2000 Sep 15;60(18):5214-22. [Content Brief]
[2]. Machida K, et al. A novel adenine nucleotide translocase inhibitor, MT-21, induces cytochrome c release by a mitochondrial permeability transition-independent mechanism. J Biol Chem. 2002 Aug 23;277(34):31243-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MT-21 Related Classifications
HY-136602 Related Classifications
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