G9a-IN-2
G9a-IN-2 (Compound 7i) is an inhibitor for histone methyltransferases G9a with IC50 of 0.024 μM. G9a-IN-2 reduces H3K9me2 levels and induces the mRNA expression of γ-globin mRNA. G9a-IN-2 shows the potential in ameliorating sickle cell disease (SCD).
For research use only. We do not sell to patients.
- CAS No.: 2648853-26-1
- Formula: C30H42N4O4
- Molecular Weight:522.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
All Histone Methyltransferase Isoforms
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Biological Activity
Chemical Information
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CAS No. 2648853-26-1
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Molecular Weight 522.68
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Formula C30H42N4O4
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SMILES
CN(CC1)CCC1OC2=CC=C(NC([C@@H](NC(C3=C(C)C(C(CC(C)(C)C4)=O)=C4N3)=O)CCCC)=O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
G9a-IN-2 Related Classifications
HY-161787 Related Classifications
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