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Referencia número: HY-147971

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Anticancer agent 75

Anticancer agent 75 is a potent anticancer agent. Anticancer agent 75 shows cytotoxicity and selectivity in cancer cell lines. Anticancer agent 75 shows cytotoxicity to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard. Anticancer agent 75 shows good activity of antiplasmodial.

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No. CAS: 2414491-13-5
Fòrmula: C₂₂H₂₄N₂O
Peso molecular:332.44

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Anticancer agent 75 Chemical Structure

No. CAS: 2414491-13-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

IC₅₀ & Target

< sup>[1]

Plasmodium

Topoisomerase II

Ver todos los productos específicos de isoformas Parasite :

Ver todos los productos específicos de isoformas Topoisomerase :

In Vitro

Anticancer agent 75 (Compounds 3h) shows good anticancer activity and at least 35 times less toxic than Doxorubicin^[1].
Anticancer agent 75 (Compounds 3h) inhibits cancer cell growth with IC₅₀ values of 333.83 µM, 13.39 µM, 15.31 µM, 15.58 µM, and 4.90 µM for HEK-293, HuCCA-1, A549, HepG2, and MOLT-3, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

No. CAS 2414491-13-5
Peso molecular 332.44
Fòrmula C₂₂H₂₄N₂O
SMILES

CC(C)CCC(C1=C(N2C)C=C(OC)C=C1)=C3C2=NC4=CC=CC=C43
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Bhornrawin Akkachairin, et al. Synthesis of Neocryptolepines and Carbocycle-Fused Quinolines and Evaluation of Their Anticancer and Antiplasmodial Activities. Journal Pre-proofs. 2020, 98: 103732. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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