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Referencia número: HY-123605

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CAY10406

CAY10406 is an inhibitor for caspase 3/7. CAY10406 inhibits the expression of 28-kDa IL-1β fragment, without significant cytotoxicity (10 μM).

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No. CAS: 2108603-03-6
Fòrmula: C₂₇H₂₃F₃N₂O₅S
Peso molecular:544.54

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

CAY10406 Chemical Structure

No. CAS: 2108603-03-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

CAY10406 is an inhibitor for caspase 3/7. CAY10406 inhibits the expression of 28-kDa IL-1β fragment, without significant cytotoxicity (10 μM)^[1].

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Chemical Information

No. CAS 2108603-03-6
Peso molecular 544.54
Fòrmula C₂₇H₂₃F₃N₂O₅S
SMILES

O=S(C1=CC=C(C(C(C2=O)=O)=C1)N2CC3=CC=CC=C3)(N4[C@@H](CCC4)COC5=CC=C(C=C5)C(F)(F)F)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Pathak S, et al., Autoimmune inner ear disease patient-associated 28-kDa proinflammatory IL-1β fragment results from caspase-7-mediated cleavage in vitro. JCI Insight. 2020 Feb 13;5(3):e130845. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CAY10406

Z-Phe-Tyr(tBu)-diazomethylketone

Fluostatin B

Z-AEVD-FMK

Ac-LEHD-AMC

Fluostatin A sodium

Z-IETD-AFC

Boc-Glu-OBzl

Ac-LETD-AFC

Ac-DNLD-AMC

Ver todos los productos específicos de isoformas Caspase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

CAY10406

Z-Phe-Tyr(tBu)-diazomethylketone

Fluostatin B

Z-AEVD-FMK

Ac-LEHD-AMC

Fluostatin A sodium

Z-IETD-AFC

Boc-Glu-OBzl

Ac-LETD-AFC

Ac-DNLD-AMC

Ver todos los productos específicos de isoformas Caspase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

CAY10406 Related Classifications

HY-123605 Related Classifications