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Referencia número: HY-14477

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UPF-1035

UPF-1035 is a selective PARP-2 inhibitor with an IC₅₀ value of 0.15 μM. UPF-1035 increases CA1 pyramidal cell loss in hippocampal and has neuroprotective activity.

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No. CAS: 370872-09-6
Fòrmula: C₁₆H₁₁NO₃
Peso molecular:265.26

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

UPF-1035 Chemical Structure

No. CAS: 370872-09-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
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Actividad biológica

Descripciòn

UPF-1035 is a selective PARP-2 inhibitor with an IC₅₀ value of 0.15 μM. UPF-1035 increases CA1 pyramidal cell loss in hippocampal and has neuroprotective activity^[1].

IC₅₀ & Target

PARP-1

9 μM (IC₅₀)

PARP-2

0.15 μM (IC₅₀)

Ver todos los productos específicos de isoformas PARP :

Chemical Information

No. CAS 370872-09-6
Peso molecular 265.26
Fòrmula C₁₆H₁₁NO₃
SMILES

O=C1C2=CC=CC(OC(C3=CC=CC=C3)=O)=C2C=CN1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. F Moroni , et al. Selective PARP-2 inhibitors increase apoptosis in hippocampal slices but protect cortical cells in models of post-ischaemic brain damage. Br J Pharmacol. 2009 Jul;157(5):854-62. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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UPF-1035

Ver todos los productos específicos de isoformas PARP

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

UPF-1035 Related Classifications

HY-14477 Related Classifications