CXCL9 - C-X-C motif chemokine ligand 9 Gene

Also Known as CMK; MIG; Humig; SCYB9; crg-10

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 4283

About CXCL9

Cytogenetic location: 4q21.1 Genomic coordinates (GRCh38): 4:76,001,275-76,007,509 (from NCBI)

This gene has 1 transcript (splice variant), 121 orthologues and 12 paralogues. Biased expression in lymph node (RPKM 167.1), appendix (RPKM 44.1) and 5 other tissues.

Summary

This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded is thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Aug 2020]

CXCL9 Products (1)

mRNA	Protein	Name
NM_002416.3	NP_002407.1	C-X-C motif chemokine 9 precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables CXCR3 chemokine receptor binding	IDA IDA: Inferred from direct assay	12782716	GOA
enables chemokine activity	IDA IDA: Inferred from direct assay	12782716	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	18275857	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA IDA: Inferred from direct assay	12782716	GOA
involved in antimicrobial humoral immune response mediated by antimicrobial peptide	IDA IDA: Inferred from direct assay	12949249	GOA
involved in chemotaxis	IDA IDA: Inferred from direct assay	12782716	GOA
involved in killing of cells of another organism	IDA IDA: Inferred from direct assay	12949249	GOA
involved in positive regulation of release of sequestered calcium ion into cytosol	IDA IDA: Inferred from direct assay	12782716	GOA
involved in regulation of cell population proliferation	IDA IDA: Inferred from direct assay	12782716	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CXCL9 Protein Structure

IL8

0
100
125 a.a.

Protein Preferred Names	Protein Names
C-X-C motif chemokine 9	chemokine (C-X-C motif) ligand 9

CXCL9 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	CXCL9	Q07325	LDLRAD1	Homo sapiens	Q5T700	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	LDLRAD1	Homo sapiens	Q5T700	Validated Y2H	32296183
Intra	CXCL9	Q07325	LDLRAD1	Homo sapiens	Q5T700	Y2H Array	32296183
Intra	CXCL9	Q07325	SFTPC	Homo sapiens	P11686	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	SFTPC	Homo sapiens	P11686	Y2H Array	31515488
Intra	CXCL9	Q07325	SFTPC	Homo sapiens	P11686	Y2H Array	25416956
Intra	CXCL9	Q07325	SFTPC	Homo sapiens	P11686	Y2H Array	32296183
Intra	CXCL9	Q07325	LSMEM2	Homo sapiens	Q8N112	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	LSMEM2	Homo sapiens	Q8N112	Validated Y2H	32296183
Intra	CXCL9	Q07325	LSMEM2	Homo sapiens	Q8N112	Y2H Array	32296183
Intra	CXCL9	Q07325	NEMP1	Homo sapiens	O14524-2	Y2H Array	32296183
Intra	CXCL9	Q07325	NEMP1	Homo sapiens	O14524-2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	TMEM237	Homo sapiens	Q96Q45-2	Validated Y2H	32296183
Intra	CXCL9	Q07325	TMEM237	Homo sapiens	Q96Q45-2	Y2H Array	32296183
Intra	CXCL9	Q07325	TMEM237	Homo sapiens	Q96Q45-2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	LRRC25	Homo sapiens	Q8N386	Y2H Array	32296183
Intra	CXCL9	Q07325	LRRC25	Homo sapiens	Q8N386	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	LRRC25	Homo sapiens	Q8N386	Validated Y2H	32296183
Intra	CXCL9	Q07325	BSCL2	Homo sapiens	J3KQ12	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	BSCL2	Homo sapiens	J3KQ12	Y2H Array	32296183
Intra	CXCL9	Q07325	CLEC2D	Homo sapiens	Q9UHP7-3	Y2H Array	32296183
Intra	CXCL9	Q07325	CLEC2D	Homo sapiens	Q9UHP7-3	Validated Y2H	32296183
Intra	CXCL9	Q07325	CLEC2D	Homo sapiens	Q9UHP7-3	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CLEC17A	Homo sapiens	Q6ZS10	Validated Y2H	32296183
Intra	CXCL9	Q07325	CLEC17A	Homo sapiens	Q6ZS10	Y2H Array	32296183
Intra	CXCL9	Q07325	CLEC17A	Homo sapiens	Q6ZS10	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CLEC7A	Homo sapiens	Q9BXN2-6	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CLEC7A	Homo sapiens	Q9BXN2-6	Validated Y2H	32296183
Intra	CXCL9	Q07325	CLEC7A	Homo sapiens	Q9BXN2-6	Y2H Array	32296183
Intra	CXCL9	Q07325	FNDC9	Homo sapiens	Q8TBE3	Validated Y2H	32296183
Intra	CXCL9	Q07325	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
Intra	CXCL9	Q07325	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	MR1	Homo sapiens	Q95460-2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	MR1	Homo sapiens	Q95460-2	Y2H Array	32296183
Intra	CXCL9	Q07325	MR1	Homo sapiens	Q95460-2	Validated Y2H	32296183
Intra	CXCL9	Q07325	PTPN5	Homo sapiens	P54829	Y2H Array	25416956
Intra	CXCL9	Q07325	TMPRSS2	Homo sapiens	O15393-2	Y2H Array	32296183
Intra	CXCL9	Q07325	TMPRSS2	Homo sapiens	O15393-2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CLEC4E	Homo sapiens	Q9ULY5	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CLEC4E	Homo sapiens	Q9ULY5	Validated Y2H	32296183
Intra	CXCL9	Q07325	CLEC4E	Homo sapiens	Q9ULY5	Y2H Array	32296183
Intra	CXCL9	Q07325	ITM2C	Homo sapiens	Q9NQX7-3	Validated Y2H	32296183
Intra	CXCL9	Q07325	ITM2C	Homo sapiens	Q9NQX7-3	Y2H Array	32296183
Intra	CXCL9	Q07325	ITM2C	Homo sapiens	Q9NQX7-3	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	FUT7	Homo sapiens	Q11130	Validated Y2H	32296183
Intra	CXCL9	Q07325	FUT7	Homo sapiens	Q11130	Y2H Array	32296183
Intra	CXCL9	Q07325	FUT7	Homo sapiens	Q11130	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	FIMP	Homo sapiens	Q96LL3	Validated Y2H	32296183
Intra	CXCL9	Q07325	FIMP	Homo sapiens	Q96LL3	Y2H Array	32296183
Intra	CXCL9	Q07325	FIMP	Homo sapiens	Q96LL3	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	ATP1B4	Homo sapiens	Q9UN42	Validated Y2H	32296183
Intra	CXCL9	Q07325	ATP1B4	Homo sapiens	Q9UN42	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	ATP1B4	Homo sapiens	Q9UN42	Y2H Array	32296183
Intra	CXCL9	Q07325	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	CXCL9	Q07325	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	AQP6	Homo sapiens	Q13520	Validated Y2H	32296183
Intra	CXCL9	Q07325	TNFSF8	Homo sapiens	P32971	Y2H Array	32296183
Intra	CXCL9	Q07325	TNFSF8	Homo sapiens	P32971	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	TM4SF18	Homo sapiens	Q96CE8	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	TM4SF18	Homo sapiens	Q96CE8	Validated Y2H	32296183
Intra	CXCL9	Q07325	TM4SF18	Homo sapiens	Q96CE8	Y2H Array	32296183
Intra	CXCL9	Q07325	RHCG	Homo sapiens	Q9UBD6	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	RHCG	Homo sapiens	Q9UBD6	Validated Y2H	32296183
Intra	CXCL9	Q07325	RHCG	Homo sapiens	Q9UBD6	Y2H Array	32296183
Intra	CXCL9	Q07325	FCGR2A	Homo sapiens	P12318-2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	FCGR2A	Homo sapiens	P12318-2	Y2H Array	32296183
Intra	CXCL9	Q07325	MUC1	Homo sapiens	P15941-11	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	MUC1	Homo sapiens	P15941-11	Y2H Array	32296183
Intra	CXCL9	Q07325	EREG	Homo sapiens	O14944	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	EREG	Homo sapiens	O14944	Y2H Array	32296183
Intra	CXCL9	Q07325	SSMEM1	Homo sapiens	Q8WWF3	Y2H Array	32296183
Intra	CXCL9	Q07325	SSMEM1	Homo sapiens	Q8WWF3	Validated Y2H	32296183
Intra	CXCL9	Q07325	SSMEM1	Homo sapiens	Q8WWF3	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CHODL	Homo sapiens	Q9H9P2	Validated Y2H	32296183
Intra	CXCL9	Q07325	CHODL	Homo sapiens	Q9H9P2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CHODL	Homo sapiens	Q9H9P2	Y2H Array	32296183
Intra	CXCL9	Q07325	EPGN	Homo sapiens	Q6UW88-2	Validated Y2H	32296183
Intra	CXCL9	Q07325	EPGN	Homo sapiens	Q6UW88-2	Y2H Array	32296183
Intra	CXCL9	Q07325	EPGN	Homo sapiens	Q6UW88-2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	LEUTX	Homo sapiens	A8MZ59	Y2H Array	32296183
Intra	CXCL9	Q07325	LEUTX	Homo sapiens	A8MZ59	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	GJB1	Homo sapiens	P08034	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	GJB1	Homo sapiens	P08034	Y2H Array	32296183
Intra	CXCL9	Q07325	TSPAN18	Homo sapiens	Q8WUV1	Validated Y2H	32296183
Intra	CXCL9	Q07325	TSPAN18	Homo sapiens	Q8WUV1	Y2H Array	32296183
Intra	CXCL9	Q07325	TSPAN18	Homo sapiens	Q8WUV1	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	BTNL9	Homo sapiens	Q6UXG8-3	Validated Y2H	32296183
Intra	CXCL9	Q07325	BTNL9	Homo sapiens	Q6UXG8-3	Y2H Array	32296183
Intra	CXCL9	Q07325	BTNL9	Homo sapiens	Q6UXG8-3	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	GPR42	Homo sapiens	O15529	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	GPR42	Homo sapiens	O15529	Y2H Array	32296183
Intra	CXCL9	Q07325	SUSD3	Homo sapiens	Q96L08	Validated Y2H	32296183
Intra	CXCL9	Q07325	SUSD3	Homo sapiens	Q96L08	Y2H Array	32296183
Intra	CXCL9	Q07325	SUSD3	Homo sapiens	Q96L08	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CLDN5	Homo sapiens	O00501	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CLDN5	Homo sapiens	O00501	Y2H Array	32296183
Intra	CXCL9	Q07325	AMIGO1	Homo sapiens	Q86WK6	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	AMIGO1	Homo sapiens	Q86WK6	Validated Y2H	32296183
Intra	CXCL9	Q07325	AMIGO1	Homo sapiens	Q86WK6	Y2H Array	32296183
Intra	CXCL9	Q07325	PF4	Homo sapiens	P02776	SPR	28381538
Intra	CXCL9	Q07325	PF4	Homo sapiens	P02776	Filter Binding	28381538
Intra	CXCL9	Q07325	CXCL14	Homo sapiens	O95715	Filter Binding	28381538
Intra	CXCL9	Q07325	TMEM106C	Homo sapiens	Q9BVX2	Validated Y2H	32296183
Intra	CXCL9	Q07325	TMEM106C	Homo sapiens	Q9BVX2	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	TMEM106C	Homo sapiens	Q9BVX2	Y2H Array	32296183
Intra	CXCL9	Q07325	FFAR2	Homo sapiens	O15552	Y2H Array	32296183
Intra	CXCL9	Q07325	FFAR2	Homo sapiens	O15552	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CCL5	Homo sapiens	P13501	SPR	28381538
Intra	CXCL9	Q07325	CCL5	Homo sapiens	P13501	Filter Binding	28381538
Intra	CXCL9	Q07325	DPP4	Homo sapiens	P27487	Enzymatic Study	18275857
Intra	CXCL9	Q07325	DPP4	Homo sapiens	P27487	Protease Assay	21314817
Intra	CXCL9	Q07325	IFNGR2	Homo sapiens	P38484	Y2H Array	32296183
Intra	CXCL9	Q07325	IFNGR2	Homo sapiens	P38484	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CD33	Homo sapiens	P20138	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CD33	Homo sapiens	P20138	Y2H Array	32296183
Intra	CXCL9	Q07325	CXCL12	Homo sapiens	P48061	SPR	28381538
Intra	CXCL9	Q07325	CXCL12	Homo sapiens	P48061	Filter Binding	28381538
Intra	CXCL9	Q07325	GORAB	Homo sapiens	Q5T7V8	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	GORAB	Homo sapiens	Q5T7V8	Y2H Array	32296183
Intra	CXCL9	Q07325	GORAB	Homo sapiens	Q5T7V8	Validated Y2H	32296183
Intra	CXCL9	Q07325	SLC10A1	Homo sapiens	Q14973	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	SLC10A1	Homo sapiens	Q14973	Validated Y2H	32296183
Intra	CXCL9	Q07325	SLC10A1	Homo sapiens	Q14973	Y2H Array	32296183
Intra	CXCL9	Q07325	MTIF3	Homo sapiens	Q9H2K0	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	MTIF3	Homo sapiens	Q9H2K0	Validated Y2H	32296183
Intra	CXCL9	Q07325	MTIF3	Homo sapiens	Q9H2K0	Y2H Array	32296183
Intra	CXCL9	Q07325	TNFSF14	Homo sapiens	O43557	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	TNFSF14	Homo sapiens	O43557	Y2H Array	32296183
Intra	CXCL9	Q07325	SYNE4	Homo sapiens	Q8N205	Y2H Prey Pooling	25416956
Intra	CXCL9	Q07325	PPBP	Homo sapiens	P02775	Filter Binding	28381538
Intra	CXCL9	Q07325	SLC39A1	Homo sapiens	Q9NY26	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	SLC39A1	Homo sapiens	Q9NY26	Validated Y2H	32296183
Intra	CXCL9	Q07325	SLC39A1	Homo sapiens	Q9NY26	Y2H Array	32296183
Intra	CXCL9	Q07325	CLDN7	Homo sapiens	O95471	Y2H Array	32296183
Intra	CXCL9	Q07325	CLDN7	Homo sapiens	O95471	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	KASH5	Homo sapiens	Q8N6L0	Validated Y2H	25416956
Intra	CXCL9	Q07325	KASH5	Homo sapiens	Q8N6L0	Y2H Prey Pooling	25416956
Intra	CXCL9	Q07325	CLDN2	Homo sapiens	P57739	Y2H Array	32296183
Intra	CXCL9	Q07325	CLDN2	Homo sapiens	P57739	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	TMED5	Homo sapiens	Q9Y3A6	Validated Y2H	32296183
Intra	CXCL9	Q07325	TMED5	Homo sapiens	Q9Y3A6	Y2H Array	32296183
Intra	CXCL9	Q07325	TMED5	Homo sapiens	Q9Y3A6	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	CCL26	Homo sapiens	Q9Y258	Filter Binding	28381538
Intra	CXCL9	Q07325	CXCL10	Homo sapiens	P02778	Filter Binding	28381538
Intra	CXCL9	Q07325	KIR2DL3	Homo sapiens	P43628	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	KIR2DL3	Homo sapiens	P43628	Y2H Array	32296183
Intra	CXCL9	Q07325	TMEM234	Homo sapiens	Q8WY98	Y2H Prey Pooling	32296183
Intra	CXCL9	Q07325	TMEM234	Homo sapiens	Q8WY98	Validated Y2H	32296183
Intra	CXCL9	Q07325	TMEM234	Homo sapiens	Q8WY98	Y2H Array	32296183
Intra	CXCL9	Q07325	CCL21	Homo sapiens	O00585	Filter Binding	28381538

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CXCL9 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7253	MIG/CXCL9 Protein, Human	Q07325 (T23-T125)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72675	MIG/CXCL9 Protein, Human (HEK293, His)	Q07325 (T23-T125)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P700050AF	Animal-Free MIG/CXCL9 Protein, Human (His)	Q07325 (T23-T125)	≥ 95%, as determined by reducing SDS-PAGE.

CXCL9 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P84505	CXCL9 Antibody (YA4202)	ICC/IF, FC, ELISA, ELISA	Human
HY-P84505A	CXCL9 Antibody (YA4202)(PBS only)	ICC/IF, FC, ELISA, ELISA	Human

Related Diseases

Diseases	Alias
Proliferative Glomerulonephritis
Paracoccidioidomycosis	Mucocutaneous-Lymphangitic Paracoccidioidomycosis Paracoccidioidal Mycosis Lobo Disease Lutz-Splendore-Almeida Disease Pcm Paracoccidioidal Granuloma South American Blastomycosis Lobomycosis Brazilian Blastomycosis Lutz Disease Brazilian Blastomycotic South American Blastomyces Infection Paracoccidioides Brasiliensis Infection Paracoccidioidomycosis Unspecified
Melioidosis	Melioidosis, Susceptibility To Acute And Fulminating Melioidosis Nightcliff Gardener'S Disease Pseudoglanders Subacute And Chronic Melioidosis Burkholderia Pseudomallei Infection Whitmore Disease Whitmore'S Disease B Pseudomallei Infection Epizootic Lymphangitis Infection Due To Burkholderia Pseudomallei Infection Due To Burkholderia Pseudomallei Nos Infection Due To Malleomyces Pseudomallei Infection Due To Pseudomonas Pseudomallei Infection Due To Pseudomonas Pseudomallei Nos Infection Due To Whitmore Bacillus Stanton Disease
Spotted Fever	Spotted Fevers Spotted Fever Group Rickettsial Disease Tick-Borne Rickettsioses Tick-Borne Typhus Nos Rocky Mountain Spotted Fever Sao Paulo Fever Sao Paulo Typhus Lone Star Spotted Fever Colombian Spotted Fever American Spotted Fever Tick Typhus Due To Rickettsia Rickettsii Rocky Mountain Tick Fever Boutonneuse Fever Mediterranean Tick Fever Fièvre Boutonneuse Mediterranean Spotted Fever Tick Typhus Due To Rickettsia Conorii African Tick Typhus Indian Tick Typhus Kenya Tick Typhus North Asian Tick Fever Siberian Tick Typhus Tick Typhus Due To Rickettsia Siberica North Asian Spotted Fever Queensland Tick Typhus Queensland Fever
Lichen Planus	Lichen Ruber Planus Lichen, Ruber Planus Ruber Planus Lp - [Lichen Planus] Lichen Planus Of Wilson Wilson Lichen Ruber
Acrodermatitis
Mycosis Fungoides	Mycosis Fungoides Lymphoma Alibert-Bazin Syndrome Granuloma Fungoides Classic Mycosis Fungoides Mycosis Fungoides, Alibert-Bazin Type
Inclusion Body Myositis	Ibm Sporadic Inclusion Body Myositis Inflammatory Myopathy Myositis, Inclusion Body Inflammatory Myopathies Sibm Myositis Inclusion Body Nonaka Myopathy Inclusion Body Myopathy, Autosomal Recessive Inclusion Body Myopathy, Autosomal Dominant Myositis Inclusion Body Myopathy, Sporadic
Lymphadenitis	Acute Lymphadenitis Chronic Lymphadenitis Adenitis Chronic Adenitis Acute Adenitis Inflammation Of Lymph Node Adenitis Nos Inflammation Of Gland Lymphatic Gland Inflammation Lymph Gland Inflammation Polyadenitis Chronic Adenitis Of Any Lymph Node Except Mesenteric Chronic Lymphadenitis Except Mesenteric Chronic Non-Specific Lymphadenitis
Encephalitis	Mumps Encephalitis Mumps Meningoencephalitis Herpes Simplex Neuroinvasion Herpetic Encephalitis Herpetic Encephalopathy Herpes Simplex Encephalitis, Myelitis Or Encephalomyelitis Encephalitis Due To Herpesviridae Encephalitis Due To Herpesvirus Herpes Encephalitis Herpesviral Encephalitis Herpes Simplex Encephalitis Hsv - [Herpes Simplex Virus] Encephalitis Herpes Virus Encephalitis Simian B Disease Simian B Disorder Encephalitis Nec Idiopathic Encephalitis
Trypanosomiasis
Smallpox	Variola Ordinary Smallpox Alastrim Amaas
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Alopecia Areata	Aa Alopecia Celsi Alopecia Circumscripta Cazenave'S Vitiligo Celsus' Vitiligo Diffuse Alopecia Jonston'S Alopecia Marginal Alopecia Pseudopelade Circumscribed Alopecia Alopecia Cicatrisata Patchy Alopecia Alopecia Aa - [Alopecia Areata] Pelade
Visceral Leishmaniasis	Kala-Azar Leishmaniasis, Visceral Infection By Visceral Leishmaniasis Leishmaniasis Visceral Sahib Disease Ponos Burdwan Fever Mard El Bicha Sirkari Disease Indian Visceral Leishmaniasis Dumdum Fever Visceral Leishmaniasis Due To Leishmania Donovani
Lymphomatoid Granulomatosis	Lyg Granulomatosis, Lymphomatoid
Severe Acute Respiratory Syndrome	Sars Sars-Cov Infection Sars-1 Sar Deficiency Sars - [Severe Acute Respiratory Syndrome]
Cryoglobulinemia	Cryoimmunoglobulinaemia
Contact Dermatitis	Contact Dermatitis/Eczema Contact Eczema Dermatitis Venenata Dermatitis, Venenata Dermatitis Contact Dermatitis, Contact
Dermatitis	Eczema Skin Inflammation Inflammatory Dermatosis
Pustular Psoriasis
Radiculopathy	Pinched Nerve Nerve Root Disorder Radiculopathy, Site Unspecified Radicular Neuropathy Radicular Syndrome Radicular Pain Radiculitis Radiculitis Nos Spinal Root Pain Nerve Root Neuritis Radiculopathy In Spondylosis
Conjunctivitis	Madras Eye Adenoviral Conjunctivitis Acute Adenoviral Follicular Conjunctivitis Inclusion Conjunctivitis Of The Adult Swimming-Pool Conjunctivitis Inflammation Of Conjunctiva Ophthalmia Acute Conjunctivitis Eye Catarrh Catarrhal Ophthalmia Koch-Weeks Conjunctivitis
Q Fever	Infection Due To Coxiella Burnetii Quadrilateral Fever Query Fever Nine Mile Fever Coxiella Burnetii Fever Q Fever Pneumonia Coxiellosis Pneumonia In Q Fever Australian Q Fever Balkan Grippe
Sarcoidosis 1	Sarcoidosis Boeck Sarcoid Besnier-Boeck-Schaumann Disease SS1 Sarcoidosis, Susceptibility To, 1 Lymphogranulomatosis Hodgkin Disease Boeck'S Disease Boeck'S Sarcoid Schaumann'S Disease Or Syndrome Hutchinson-Boeck Disease Or Syndrome
Macrophage Activation Syndrome
Allergic Contact Dermatitis	Dermatitis, Allergic Contact Contact Dermatitis, Allergic Dermatitis Allergic Contact Allergic Contact Eczema Acd - [Allergic Contact Dermatitis] Allergic Contact Dermatitis, Unspecified Cause Allergic Dermatitis Allergic Eczema Allergy Dermatitis Allergy Eczema Allergic Contact Eczema Due To Clothing Or Footwear Perfume Allergic Contact Dermatitis Allergic Contact Dermatitis Due To Cosmetics Allergic Contact Eczema Due To Cosmetics Or Fragrances Allergic Contact Eczema Due To Dental Materials Allergic Contact Eczema Due To Food Flavours Or Additives Allergic Contact Eczema Due To Hairdressing Products Allergic Contact Eczema Due To Metals Or Metal Salts Allergic Contact Eczema Due To Proteins Allergic Contact Eczema Due To Plastics Or Resin Systems Allergic Contact Eczema Due To Preservatives Or Biocides Allergic Contact Eczema Due To Rubber Chemicals Rubber Dermatitis Allergic Contact Eczema Due To Systemic Medicaments Allergic Contact Eczema Due To Topical Medicaments Allergic Contact Dermatitis Due To Drugs In Contact With Skin
Scleredema Adultorum	Scleredema Buschke'S Scleredema Scleredema Adultorum Of Buschke Scleredema Diabeticorum Scleredema Diabeticorum Of Buschke Buschke Scleredema
Mycobacterium Tuberculosis 1	Tuberculosis Tuberculoma Tuberculosis, Susceptibility To Mycobacterium Tuberculosis, Susceptibility To, 1 Mtbs1 TB
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To Cryptogenic Fibrosing Alveolitis ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Glomerulonephritis	Bright'S Disease
Psoriasis
Myocarditis	Myocardial Inflammation Inflammatory Cardiomyopathy
Keratitis, Hereditary	Keratitis Autosomal Dominant Keratitis Hereditary Keratitis Dominantly Inherited Keratitis Keratitis Hereditary KERH
Dermatitis, Atopic	Atopic Dermatitis Atopic Eczema Dermatitis, Atopic, Susceptibility To, 1 Atod Eczema, Atopic Dermatitis, Atopic 1 Allergic Dermatitis Atopic Neurodermatitis Besnier'S Prurigo Dermatitis, Atopic, 1 Dermatitis Atopic Eczema Besnier Prurigo
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Bacterial Infectious Disease	Bacterial Infections Bacterial Infection Nos Disease Caused By Bacteria Bacterial Disease Or Disorder
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Co-Trimoxazole Allergy	Bactrim Allergy Cotrimoxazol Allergy Tmp/Smx Allergy Trimethoprim/Sulfamethoxazole Allergy
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P991610	S-095029	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N7688	Regaloside B	Inhibitor	99.90%	Unkown
HY-165428	SCH-900875	Inhibitor	98.16%	Unkown
HY-162415	CSF1R-IN-22		/	Unkown
HY-168971	Paeoniflorin-6′-O-benzene sulfonate		/	Unkown
HY-181877	IHCH-3185		/	Unkown
HY-P10301	CXCL9(74-103)		/	Unkown
HY-RS03396	CXCL9 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W505771	Seselin	Inhibitor	99.55%	Unkown
HY-167884	PF-1367550	Inhibitor	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990255	Anti-Mouse CXCL9/MIG Antibody (MIG-2F5.5)	Inhibitor	95.00%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CXCL9	VGNC	VGNC:100215
Bos taurus	CXCL9	VGNC	VGNC:27854
Mus musculus	CXCL9	MGD	MGI:1352449
Rattus norvegicus	CXCL9	RGD	RGD:628798
Felis catus	CXCL9	VGNC	VGNC:107324
Others	CXCL9	NCBI