2. Apoptosis Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. CDK Glutathione Peroxidase
  4. GPX4/CDK-IN-1

GPX4/CDK-IN-1 (Compound B9) is a dual inhibitor of GPX4 and CDK, with IC50 values of 542.5 nM, 191.2 nM and 68.1 nM for GPX4, CDK4 and CDK6, reapectively. GPX4/CDK-IN-1 shows strong cancer cell growth inhibition in vivo.

For research use only. We do not sell to patients.

GPX4/CDK-IN-1 Chemical Structure

GPX4/CDK-IN-1 Chemical Structure

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GPX4/CDK-IN-1 Related Antibodies

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Description

GPX4/CDK-IN-1 (Compound B9) is a dual inhibitor of GPX4 and CDK, with IC50 values of 542.5 nM, 191.2 nM and 68.1 nM for GPX4, CDK4 and CDK6, reapectively. GPX4/CDK-IN-1 shows strong cancer cell growth inhibition in vivo[1].

Molecular Weight

962.90

Formula

C48H45Cl2N9O7S
SMILES

O=C(/C1=C2NC3=C(C\2=N/OCCCNC(CCN4N=NC(COC5=C(C=C(C=C5)N(C(CCl)=O)C(C6=CC=CS6)C(NCCC7=CC=CC=C7)=O)Cl)=C4)=O)C=CC=C3)NC8=C1C=CC(OC)=C8
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GPX4/CDK-IN-1 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GPX4/CDK-IN-1CDKGlutathione PeroxidaseCyclin dependent kinasecancerGPX4CDK4CDK6Inhibitorinhibitorinhibit

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