HDAC6-IN-53
HDAC6-IN-53 (Compound W28) is an inhibitor targeting histone deacetylase 6 (HDAC6) with an IC50 of 19.65 nM. HDAC6-IN-53 exerts the activity of inhibiting the phenotype of idiopathic pulmonary fibrosis (IPF) by suppressing the collagen expression induced by TGF-β1, and it has demonstrated a good therapeutic effect in a mouse model of pulmonary fibrosis induced by Bleomycin (HY-17565A). HDAC6-IN-53 can be used in the research of idiopathic pulmonary fibrosis and other related pulmonary fibrosis diseases.
For research use only. We do not sell to patients.
- CAS No.: 3081880-03-4
- Formula: C26H24BrN3O4
- Molecular Weight:522.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC6 19.65 nM (IC50) |
Chemical Information
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CAS No. 3081880-03-4
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Molecular Weight 522.39
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Formula C26H24BrN3O4
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SMILES
O=C(C1=CC=C(Br)C=C1)NCCC2=CN(CC3=CC=C(C(NO)=O)C=C3)C4=CC=C(OC)C=C42
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HDAC6-IN-53 Related Classifications
HY-173184 Related Classifications
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