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Cat. No.: HY-175401

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ICP-103

ICP-103 (Compound 3K) is a highly selective protein kinase C (PKC) inhibitor with an IC₅₀ of 30 nM. ICP-103 is promising for research of cancers.

For research use only. We do not sell to patients.

CAS No.: 153997-72-9
Formula: C₂₄H₁₆N₄O₂
Molecular Weight:392.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

ICP-103 Chemical Structure

CAS No.: 153997-72-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

ICP-103 (Compound 3K) is a highly selective protein kinase C (PKC) inhibitor with an IC₅₀ of 30 nM. ICP-103 is promising for research of cancers^[1]^[2].

All PKC Isoforms :

Chemical Information

CAS No. 153997-72-9
Molecular Weight 392.41
Formula C₂₄H₁₆N₄O₂
SMILES

N#CCCN(C1=C2C(C(NC3=O)=O)=C3C4=C1N(C)C5=C4C=CC=C5)C6=C2C=CC=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kleinschroth J, Hartenstein J, Rudolph C, et al. Novel indolocarbazole protein kinase C inhibitors with improved biochemical and physicochemical properties[J]. Bioorganic & Medicinal Chemistry Letters, 1995, 5(1): 55-60.

[2]. Roy S, Eastman A, Gribble G W. Synthesis of 7‐keto‐Gö6976 (ICP‐103)[J]. Synthetic communications, 2005, 35(4): 595-601.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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References

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ICP-103

All PKC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ICP-103 Related Classifications

HY-175401 Related Classifications