Abaperidone
Abaperidone is a potent antagonist of 5-HT2A receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 183849-43-6
- 分子式: C25H25FN2O5
- 分子量:452.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-15780
BrexpiprazoleAntipsychotic Agent -
HY-14763
CariprazineD3/D2/5-HT Modulator -
HY-N0096
RotundineDopamine Receptor Antagonist -
HY-B0031
Quetiapine hemifumarate5-HT Agonist/D2 Antagonist -
HY-14763A
Cariprazine hydrochlorideDopamine Receptor Modulator -
HY-B0031R
Quetiapine hemifumarate (Standard) -
HY-15780R
Brexpiprazole (Standard)Antipsychotic Agent -
HY-14763R
Cariprazine (Standard)D3/D2/5-HT Modulator
生物活性
製品説明
IC50 & Target
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5-HT2A Receptor |
D2 Receptor 17 nM (IC50) |
5-HT2A Receptor 6.2 nM (IC50) |
体外実験
Abaperidone possesses good affinity for dopamine D2 receptors, together with a greater affinity for 5-HT2 receptors with IC50 of 17 and 6.2 nM, reaspectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 183849-43-6
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分子量 452.47
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分子式 C25H25FN2O5
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SMILES
O=C1C(CO)=COC2=CC(OCCCN3CCC(C4=NOC5=C4C=CC(F)=C5)CC3)=CC=C12
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Bolós J, et al. 7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics. 2. Pharmacological profile of 7-[3-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)-piperidin-1-yl]propoxy]-3-(hydroxymeth yl)chromen -4-one (abaperidone, FI-8602). J Med Chem. 1998 Dec 31;41(27):5402-9. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Abaperidone 関連分類
HY-101619 関連分類
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