Abaperidone
Abaperidone is a potent antagonist of 5-HT2A receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 183849-43-6
- 分子式: C25H25FN2O5
- 分子量:452.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-15780
BrexpiprazoleAntipsychotic Agent -
HY-14763
CariprazineD3/D2/5-HT Modulator -
HY-N0096
RotundineDopamine Receptor Antagonist -
HY-B0031
Quetiapine hemifumarate5-HT Agonist/D2 Antagonist -
HY-14763A
Cariprazine hydrochlorideDopamine Receptor Modulator -
HY-B0031R
Quetiapine hemifumarate (Standard) -
HY-15780R
Brexpiprazole (Standard)Antipsychotic Agent -
HY-14763R
Cariprazine (Standard)D3/D2/5-HT Modulator
生物活性
製品説明
IC50 & Target
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D2 Receptor 17 nM (IC50) |
5-HT2A Receptor 6.2 nM (IC50) |
体外実験
Abaperidone possesses good affinity for dopamine D2 receptors, together with a greater affinity for 5-HT2 receptors with IC50 of 17 and 6.2 nM, reaspectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 183849-43-6
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分子量 452.47
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分子式 C25H25FN2O5
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SMILES
O=C1C(CO)=COC2=CC(OCCCN3CCC(C4=NOC5=C4C=CC(F)=C5)CC3)=CC=C12
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Bolós J, et al. 7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics. 2. Pharmacological profile of 7-[3-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)-piperidin-1-yl]propoxy]-3-(hydroxymeth yl)chromen -4-one (abaperidone, FI-8602). J Med Chem. 1998 Dec 31;41(27):5402-9. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Abaperidone 関連分類
HY-101619 関連分類
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