Revexepride
Based on 1 publication(s) in Google Scholar
Revexepride is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease.
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- 純度: 99.84%
- CAS 番号: 219984-49-3
- 分子式: C21H32ClN3O4
- 分子量:425.95
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Revexepride
More5-HT Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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5-HT4 Receptor |
CYP3A4 |
The human CYP isoenzymes are involved in the metabolism of revexepride, which is mainly metabolized in vitro in humans by CYP3A4 (99.9%) with a minor contribution of CYP2D6 (0.1%). Revexepride exhibits direct inhibition of human CYP3A4 in vitro with IC50 values of 16-49 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 219984-49-3
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性状 Solid
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分子量 425.95
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分子式 C21H32ClN3O4
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Color White to yellow
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SMILES
O=C(C1=C(OC(C)(C)C2)C2=C(N)C(Cl)=C1)NC[C@H]3[C@H](O)CN(CCCOC)CC3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (234.77 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3477 mL | 11.7385 mL | 23.4769 mL | 58.6923 mL |
| 5 mM | 0.4695 mL | 2.3477 mL | 4.6954 mL | 11.7385 mL | |
| 10 mM | 0.2348 mL | 1.1738 mL | 2.3477 mL | 5.8692 mL | |
| 15 mM | 0.1565 mL | 0.7826 mL | 1.5651 mL | 3.9128 mL | |
| 20 mM | 0.1174 mL | 0.5869 mL | 1.1738 mL | 2.9346 mL | |
| 25 mM | 0.0939 mL | 0.4695 mL | 0.9391 mL | 2.3477 mL | |
| 30 mM | 0.0783 mL | 0.3913 mL | 0.7826 mL | 1.9564 mL | |
| 40 mM | 0.0587 mL | 0.2935 mL | 0.5869 mL | 1.4673 mL | |
| 50 mM | 0.0470 mL | 0.2348 mL | 0.4695 mL | 1.1738 mL | |
| 60 mM | 0.0391 mL | 0.1956 mL | 0.3913 mL | 0.9782 mL | |
| 80 mM | 0.0293 mL | 0.1467 mL | 0.2935 mL | 0.7337 mL | |
| 100 mM | 0.0235 mL | 0.1174 mL | 0.2348 mL | 0.5869 mL |
Revexepride 関連分類
HY-U00373 関連分類
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