Capricostatin A
Capricostatin A is a glycosylated heteromeric depsipeptide and Antibacterial agent. Capricostatin A is present in the fungus Austroacremonium gemini MST-FP2131. Capricostatin A inhibits the growth of Gram-positive bacteria, including Bacillus subtilis, Staphylococcus aureus, and MRSA. Capricostatin A exhibits no antifungal activity against Saccharomyces cerevisiae and no cytotoxicity against mammalian cells. Capricostatin A can be used in the research of bacterial infections caused by Bacillus subtilis and Staphylococcus aureus.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C36H50O12
- 分子量:674.78
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
Fungal Metabolite |
体外実験
Capricostatin A inhibits the growth of Bacillus subtilis, Staphylococcus aureus, and Methicillin (HY-121544)-resistant S. aureus with MIC values of 1.6 μg mL−1, 3.1 μg mL−1, and 6.3 μg mL−1, respectively, but does not inhibit Saccharomyces cerevisiae, mouse myeloma NS-1 cells, or neonatal foreskin fibroblast cells at the tested concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 674.78
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分子式 C36H50O12
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SMILES
OC[C@@H](O[C@H]1OC2=CC(CCCCCCC/C=C\CCCCCC)=C(C(OC(C=C3C)=CC(O)=C3C(O)=O)=O)C(O)=C2)[C@@H]([C@@H]([C@H]1O)O)O
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Structure Classification
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Initial Source
Austroacremonium gemini
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- Capricostatin A
- Bacterial
- Endogenous Metabolite
- Antibiotic
- mammalian cells
- neonatal foreskin fibroblast cells
- Bacillus subtilis
- Saccharomyces cerevisiae
- methicillin-resistant S. aureus (MRSA)
- bacterial infections
- mouse myeloma NS-1 cells
- Staphylococcus aureus
- Gram-positive bacteria
- Austroacremonium gemini MST-FP2131
- Inhibitor
- inhibitor
- inhibit