Cyclam
Based on 1 publication(s) in Google Scholar
Cyclam is a metal chelator that forms metal complexes with a variety of metal ions. Cyclam metal complexes exhibits anti-HIV (such as AMD3100), nitric oxide (NO) releasing and scavenging (such as Zn(II)-Cyclam and Ru(II)-Cyclam), and SOD mimetic (such as Mn(III)-Cyclam and Zn(II)-Cyclam) activities.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 295-37-4
- 分子式: C10H24N4
- 分子量:200.33
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Cyclam
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>50 μM
Compound: Cyclam
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Cytotoxicity against human A549 cells incubated for 24 hrs by sulforhodamine B assay
Cytotoxicity against human A549 cells incubated for 24 hrs by sulforhodamine B assay
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[PMID: 26211460] |
| HCT-116 | IC50 |
>50 μM
Compound: Cyclam
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Cytotoxicity against human HCT116 cells incubated for 24 hrs by sulforhodamine B assay
Cytotoxicity against human HCT116 cells incubated for 24 hrs by sulforhodamine B assay
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[PMID: 26211460] |
| HeLa | IC50 |
>50 μM
Compound: Cyclam
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Cytotoxicity against human HeLa cells incubated for 24 hrs by sulforhodamine B assay
Cytotoxicity against human HeLa cells incubated for 24 hrs by sulforhodamine B assay
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[PMID: 26211460] |
| MT4 | CC50 |
>1248 μM
Compound: 42
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Concentration required to reduce the viability of mock-infected MT-4 cells
Concentration required to reduce the viability of mock-infected MT-4 cells
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[PMID: 7830280] |
| MT4 | EC50 |
150 μM
Compound: 42
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Concentration required to protect the virus infected cells against viral cytopathicity was measured on HIV-2(ROD) virus strain in MT-4 cells
Concentration required to protect the virus infected cells against viral cytopathicity was measured on HIV-2(ROD) virus strain in MT-4 cells
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[PMID: 7830280] |
| MT4 | EC50 |
399 μM
Compound: 42
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Concentration required to protect the virus infected cells against viral cytopathicity was measured on HIV-1(IIIB) virus strain in MT-4 cells
Concentration required to protect the virus infected cells against viral cytopathicity was measured on HIV-1(IIIB) virus strain in MT-4 cells
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[PMID: 7830280] |
化学情報
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CAS 番号 295-37-4
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性状 Solid
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分子量 200.33
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分子式 C10H24N4
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Color White to yellow
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SMILES
N1CCNCCCNCCNCCC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
溶剤 & 溶解度
H2O : 20 mg/mL (99.84 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.9918 mL | 24.9588 mL | 49.9176 mL | 124.7941 mL |
| 5 mM | 0.9984 mL | 4.9918 mL | 9.9835 mL | 24.9588 mL | |
| 10 mM | 0.4992 mL | 2.4959 mL | 4.9918 mL | 12.4794 mL | |
| 15 mM | 0.3328 mL | 1.6639 mL | 3.3278 mL | 8.3196 mL | |
| 20 mM | 0.2496 mL | 1.2479 mL | 2.4959 mL | 6.2397 mL | |
| 25 mM | 0.1997 mL | 0.9984 mL | 1.9967 mL | 4.9918 mL | |
| 30 mM | 0.1664 mL | 0.8320 mL | 1.6639 mL | 4.1598 mL | |
| 40 mM | 0.1248 mL | 0.6240 mL | 1.2479 mL | 3.1199 mL | |
| 50 mM | 0.0998 mL | 0.4992 mL | 0.9984 mL | 2.4959 mL | |
| 60 mM | 0.0832 mL | 0.4160 mL | 0.8320 mL | 2.0799 mL | |
| 80 mM | 0.0624 mL | 0.3120 mL | 0.6240 mL | 1.5599 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Cyclam 関連分類
HY-D0179 関連分類
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