Evifacotrep
Based on 1 Customer Validation
Evifacotrep, a short transient receptor potential channel 5 and 4 (TRPC5/TRPC4) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases. Evifacotrep targets to TRPC5/TRPC4 with IC50s ≤50 nM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.65%
- CAS 番号: 2413739-88-3
- 分子式: C18H12ClF4N5O2
- 分子量:441.77
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
TRPC5[1]
Evifacotrep (1 μM; 24 h) inhibits cell growth in ICLN-1694 cells(HEK-TRExhTRPC4)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2413739-88-3
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性状 Solid
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分子量 441.77
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分子式 C18H12ClF4N5O2
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Color White to off-white
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SMILES
O=C1NN=CC(N2CC3=C(CC2)C(OC4=CC=C(C=C4C(F)(F)F)F)=NC=N3)=C1Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (113.18 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. WO2020061162
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2636 mL | 11.3181 mL | 22.6362 mL | 56.5905 mL |
| 5 mM | 0.4527 mL | 2.2636 mL | 4.5272 mL | 11.3181 mL | |
| 10 mM | 0.2264 mL | 1.1318 mL | 2.2636 mL | 5.6591 mL | |
| 15 mM | 0.1509 mL | 0.7545 mL | 1.5091 mL | 3.7727 mL | |
| 20 mM | 0.1132 mL | 0.5659 mL | 1.1318 mL | 2.8295 mL | |
| 25 mM | 0.0905 mL | 0.4527 mL | 0.9054 mL | 2.2636 mL | |
| 30 mM | 0.0755 mL | 0.3773 mL | 0.7545 mL | 1.8864 mL | |
| 40 mM | 0.0566 mL | 0.2830 mL | 0.5659 mL | 1.4148 mL | |
| 50 mM | 0.0453 mL | 0.2264 mL | 0.4527 mL | 1.1318 mL | |
| 60 mM | 0.0377 mL | 0.1886 mL | 0.3773 mL | 0.9432 mL | |
| 80 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7074 mL | |
| 100 mM | 0.0226 mL | 0.1132 mL | 0.2264 mL | 0.5659 mL |
Evifacotrep 関連分類
HY-132813 関連分類
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