HDAC-IN-64
Based on 1 publication(s) in Google Scholar
HDAC-IN-64 (Compound 13) is a HDAC inhibitor. HDAC-IN-64 inhibits HDAC4/5/6/7/9 with IC50s of 24, 45, 85, 31, 37 nM. HDAC-IN-64 has anti-proliferative activity and anti-migration properties on prostate cancer (PCA) cells. HDAC-IN-64 inhibits LNCaP and RWPE-1 cell growth with GI50 of 0.32 and 1.1 μM respectively.
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- CAS 番号: 3052688-17-9
- 分子式: C15H8ClF4N7O
- 分子量:413.72
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 HDAC-IN-64
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生物活性
24, 45, 85, 31, 37 nM (HDAC4/5/6/7/9)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LNCaP | GI50 |
0.32 μM
Compound: 13
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Antiproliferative activity against human LNCaP cells assessed as growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human LNCaP cells assessed as growth inhibition incubated for 72 hrs by MTT assay
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[PMID: 37633202] |
| RWPE-1 | GI50 |
1.1 μM
Compound: 13
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Antiproliferative activity against human RWPE-1 cells assessed as growth inhibition incubated for 72 hrs by MTT assay
Antiproliferative activity against human RWPE-1 cells assessed as growth inhibition incubated for 72 hrs by MTT assay
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[PMID: 37633202] |
化学情報
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CAS 番号 3052688-17-9
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分子量 413.72
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分子式 C15H8ClF4N7O
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SMILES
NC1=NC(Cl)=C2N=CN(CC3=CC=C(C4=NOC(C(F)(F)F)=N4)C=C3F)C2=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HDAC-IN-64 関連分類
HY-156003 関連分類
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