IKK2-IN-4
Based on 1 Customer Validation
IKK2-IN-4 (compound 4) is a potent IKK-2 inhibitor, with an IC50 of 25 nM. IKK2-IN-4 can inhibit the LPS-induced production of TNFα in PBMCs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.51%
- CAS 番号: 354811-10-2
- 分子式: C12H11N3O2S
- 分子量:261.30
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
生物活性
製品説明
IC50 & Target
[1]|
IKK-2 25 nM (IC50) |
化学情報
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CAS 番号 354811-10-2
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性状 Solid
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分子量 261.30
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分子式 C12H11N3O2S
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Color Off-white to pink
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SMILES
O=C(C1=C(NC(N)=O)SC(C2=CC=CC=C2)=C1)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (382.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8270 mL | 19.1351 mL | 38.2702 mL | 95.6755 mL |
| 5 mM | 0.7654 mL | 3.8270 mL | 7.6540 mL | 19.1351 mL | |
| 10 mM | 0.3827 mL | 1.9135 mL | 3.8270 mL | 9.5675 mL | |
| 15 mM | 0.2551 mL | 1.2757 mL | 2.5513 mL | 6.3784 mL | |
| 20 mM | 0.1914 mL | 0.9568 mL | 1.9135 mL | 4.7838 mL | |
| 25 mM | 0.1531 mL | 0.7654 mL | 1.5308 mL | 3.8270 mL | |
| 30 mM | 0.1276 mL | 0.6378 mL | 1.2757 mL | 3.1892 mL | |
| 40 mM | 0.0957 mL | 0.4784 mL | 0.9568 mL | 2.3919 mL | |
| 50 mM | 0.0765 mL | 0.3827 mL | 0.7654 mL | 1.9135 mL | |
| 60 mM | 0.0638 mL | 0.3189 mL | 0.6378 mL | 1.5946 mL | |
| 80 mM | 0.0478 mL | 0.2392 mL | 0.4784 mL | 1.1959 mL | |
| 100 mM | 0.0383 mL | 0.1914 mL | 0.3827 mL | 0.9568 mL |