M344 (GMP)
Based on 1 Customer Validation
M344 (GMP) (D 237) (GMP) is the GMP level of M344 (HY-13506). GMP level of small molecules can be used as auxiliary reagents in cell therapy. M344 is a kind of histone acetylation enzyme inhibitor.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 251456-60-7
- 分子式: C16H25N3O3
- 分子量:307.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
2.3 μM
Compound: 23
|
Concentration required to inhibit the epidermoid A431 cell growth by 50%, P53 status of cell line used was wild-type.
Concentration required to inhibit the epidermoid A431 cell growth by 50%, P53 status of cell line used was wild-type.
|
[PMID: 11831887] |
| A549 | IC50 |
0.8 μM
Compound: 23
|
Concentration required to inhibit the lung A549 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the lung A549 cell growth by 50%,P53 status of cell line used was wild-type.
|
[PMID: 11831887] |
| HCT-116 | IC50 |
0.2 μM
Compound: 23
|
Concentration required to inhibit the colon HCT116 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the colon HCT116 cell growth by 50%,P53 status of cell line used was wild-type.
|
[PMID: 11831887] |
| HCT-116 | IC50 |
0.21 μM
Compound: 23
|
Concentration required to inhibit the HCT116 cell growth by 50%.
Concentration required to inhibit the HCT116 cell growth by 50%.
|
[PMID: 11831887] |
| LS174T | IC50 |
1.5 μM
Compound: 23
|
Concentration required to inhibit the colon LS 174T cell growth by 50%,P53 status of cell line used was mutant-type.
Concentration required to inhibit the colon LS 174T cell growth by 50%,P53 status of cell line used was mutant-type.
|
[PMID: 11831887] |
| NCI-H1299 | IC50 |
3.9 μM
Compound: 23
|
Concentration required to inhibit the lung H1299 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the lung H1299 cell growth by 50%,P53 status of cell line used was wild-type.
|
[PMID: 11831887] |
| SW-620 | IC50 |
0.7 μM
Compound: 23
|
Concentration required to inhibit the colon SW 620 cell growth by 50%,P53 status of cell line used was mutant-type.
Concentration required to inhibit the colon SW 620 cell growth by 50%,P53 status of cell line used was mutant-type.
|
[PMID: 11831887] |
| T-24 | IC50 |
3.8 μM
Compound: 23
|
Concentration required to inhibit the bladder T24 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the bladder T24 cell growth by 50%,P53 status of cell line used was wild-type.
|
[PMID: 11831887] |
化学情報
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CAS 番号 251456-60-7
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性状 Solid
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分子量 307.39
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分子式 C16H25N3O3
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Color White to off-white
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SMILES
O=C(NCCCCCCC(NO)=O)C1=CC=C(N(C)C)C=C1
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別名
D 237 (GMP); MS 344 (GMP)
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
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データシート (264 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)