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Picankibart

(別名: IBI-112)
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Based on 1 Customer Validation

Picankibart is a human-derived IgG1κ antibody targeting IL23A. Picankibart specifically binds to the IL23 p19 subunit and exerts an anti-inflammatory effect by blocking the IL23-mediated signaling pathway.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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  • 純度: 98.00%
  • CAS 番号: 2622900-74-5
  • 分子量:144.744 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Picankibart
  • Experimental Validation Results for Picankibart
  • Experimental Validation Results for Picankibart
  • Picankibart Chemical Structure
    Picankibart 構造式
CAS 番号: 2622900-74-5
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Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Picankibart on AHC2 biosensor, can bind Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293, His, HY-P74874) with an affinity constant of 7.207E-11 M as determined in BLI assay.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling IL-23A (red) with Picankibart (anti-IL-23A) (HY-P990057). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Picankibart Chemical Structure
    1/16
  • Picankibart
  • Loaded Picankibart on AHC2 biosensor, can bind Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293, His, HY-P74874) with an affinity constant of 7.207E-11 M as determined in BLI assay.
  • Flow Cytometry analysis of Raji cells labelling IL-23A (red) with Picankibart (anti-IL-23A) (HY-P990057). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).