SETDB1-IN-1
SETDB1-IN-1 is a SETDB1 inhibitor with an IC50 of 16 μM. SETDB1-IN-1 inhibits histone methyltransferase) activity via SAM-competitive and peptide-dependent mechanisms. SETDB1-IN-1 is applicable to research related to melanoma, lung cancer, liver cancer, breast cancer and prostate cancer.
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- CAS 番号: 2585194-96-1
- 分子式: C12H18ClFN6O2S
- 分子量:364.83
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Histone Methyltransferase アイソフォーム固有の製品をすべて表示
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生物活性
SETDB1-IN-1 (Compound 7) exhibits limited selectivity in a panel of 16 purified methyltransferases, and shows potent inhibitory activity against SETDB1, SUV39H1, SUV39H2, PRMT7 and PRMT1[1].
SETDB1-IN-1 is a peptide-dependent, SAM-competitive inhibitor of purified recombinant SETDB1 (570-1291)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2585194-96-1
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分子量 364.83
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分子式 C12H18ClFN6O2S
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SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](F)[C@H](O)[C@@H](CSCCN)O3.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)