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Cat. No.: HY-101225A

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8 Hydroxy PIPAT

8 Hydroxy PIPAT is a 5-HT_1A receptor agonist that promotes histamine release. 8 Hydroxy PIPAT selectively activates 5-HT_1A receptors, thereby triggering mast cell degranulation and histamine release. 8 Hydroxy PIPAT is applicable to research related to irritable bowel syndrome.

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CAS No.: 159651-91-9
화학식: C₁₆H₂₂INO
분자량:371.26

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

8 Hydroxy PIPAT Chemical Structure

CAS No.: 159651-91-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
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Biological Activity

제품 설명

IC₅₀ & Target^[1]

5-HT_1A Receptor

All 5-HT Receptor Isoforms :

All Histamine Receptor Isoforms :

In Vitro

8 Hydroxy PIPAT oxalate (20 µM; 10 min) potently stimulates histamine release from full-thickness human jejunal segments via activation of 5-HT_1A receptors^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 159651-91-9
분자량 371.26
화학식 C₁₆H₂₂INO
SMILES

OC1=C2C(CCC(N(C/C=C/I)CCC)C2)=CC=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Wang GD, et al. Mast cell expression of the serotonin1A receptor in guinea pig and human intestine. Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G855-63.

Calculators

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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8 Hydroxy PIPAT

All 5-HT Receptor Isoforms

All Histamine Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

8 Hydroxy PIPAT Related Classifications

HY-101225A Related Classifications