Copy Link Print Information

AICAR phosphate

(Synonyms: Acadesine phosphate; AICA Riboside phosphate)
226 Cited Publications
고객리뷰

Based on 226 publication(s) in Google Scholar

AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy, YAP and mitophagy inhibitor.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: 99.97%
  • CAS No.: 681006-28-0
  • 화학식: C9H17N4O9P
  • 분자량:356.23
  • 보관:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • AICAR phosphate Chemical Structure
    AICAR phosphate Chemical Structure
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
  • Experimental Validation Results for AICAR phosphate
CAS No.: 681006-28-0
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of AICAR phosphate:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 용액&용해도
  • Protocol
  • 순도&문서
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) AICAR phosphate

More
Customer Validation & Images
RT-PCRWB
  • WB
  • WB
  • WB
  • WB
  • WB
  • RT-PCR
  • WB
  • WB
  • WB
  • WB

All AMPK Isoforms

More

All YAP Isoforms

More

All Endogenous Metabolite Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • AICAR phosphate Chemical Structure
    AICAR phosphate Chemical Structure
    1/16
  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Antioxid Redox Signal. 2024 Jan;40(1-3):16-39. [Abstract]

    Customer Validation
     AICAR (0.5 mM; 12 h) significantly increases the expression of Mfn2 in BUMPT Cells.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2018 May 1;9(5):515. [Abstract]

    Customer Validation
     Protein expression levels of AMPKα, p-AMPKα-thr172, p-ACC-ser79, LC3, Beclin-1, ATG5 and ATG7 in WT MSCs or control CrispCas MSCs, or AMPKα DKO MSCs before and after treatment with FAC or AICAR.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Int J Mol Med. 2018 May;41(5):2535-2544. [Abstract]

    Customer Validation
     Cells are treated with AICAR and AICAR (A++, 10 μM) + Compound C (C++, 1 μM) for 24 h, after which western blot analysis is performed.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Int J Mol Med. 2018 May;41(5):2535-2544. [Abstract]

    Customer Validation
     MC3T3-E1 cells are treated with AICAR (10 μM) in the presence or absence of 3-MA (5 mM) or CQ (10 μM) for 24 h, after which western blot analysis is conducted.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2018 Apr 16:9:345. [Abstract]

    Customer Validation
     AMP-activated protein kinase (AMPK) activation by AST blunts dysfunction of lipid metabolism and resistance in HepG2 cells. Representative bands of SREBP-1c nuclear protein and cytoplasmic proteins are visualized in the immunoblotting assay.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2018 Apr 16:9:345. [Abstract]

    Customer Validation
     AMP-activated protein kinase activation by AST inhibits the expression of sterol regulatory element binding protein-1c (SREBP-1c) and SREBP-1c related genes. AST promotes AMPKa1 mRNA expression, AMPKa2 mRNA expression, and suppresses the expression of SREBP-1c, and its downstream genes FAS, ACC1, and also AMPK downstream gene SCD1.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Front Pharmacol. 2018 Jul 16:9:761. [Abstract]

    Customer Validation
     Epithelial cells from colon tissue are extracted from mice in each group (n=6-8 per group) and protein level of p-AMPK (Thr172) and AMPKα1/2 are measured by western blot.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3723-3738. [Abstract]

    Customer Validation
     The effect of AICAR on the expression of AMPK, p-AMPK, mTOR, p-mTOR, and autophagy-related protein by Western blot analysis.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: J Cell Physiol. 2018 Dec;233(12):9701-9715. [Abstract]

    Customer Validation
     HUVECs are pretreated with Compound C (5, 10, or 20 μM) for 18 hr or AICAR (1, 2, or 4 mM) for 1 hr, and then exposed to LSS for 30 min.

  • 1/16

    AICAR phosphate purchased from MedChemExpress. Usage Cited in: Acta Biochim Biophys Sin (Shanghai). 2018 Feb 1;50(2):144-155. [Abstract]

    Customer Validation
     Raw264.7 macrophages with serum deprivation are treated with 50 μM Rg1 for 48 h in absence or presence of compound C (10 mM) or AICAR (250 μM). Western blots of the protein expressions of Atg5, Beclin1, LC3, and p62/SQSMT1.

  • AICAR phosphate