Copy Link Print Information

Diphenyleneiodonium chloride

(Synonyms: DPI)
66 Cited Publications
고객리뷰

Based on 66 publication(s) in Google Scholar

Diphenyleneiodonium chloride is a NADPH oxidase (NOX) inhibitor and also functions as a TRPA1 activator with an EC50 of 1 to 3 μM. Diphenyleneiodonium chloride selectively inhibits intracellular reactive oxygen species.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity : 99.88%
  • CAS No.: 4673-26-1
  • 화학식: C12H8ClI
  • 분자량:314.55
  • 보관:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)

  • Diphenyleneiodonium chloride Chemical Structure
    Diphenyleneiodonium chloride Chemical Structure
  • Experimental Validation Results for Diphenyleneiodonium chloride
  • Experimental Validation Results for Diphenyleneiodonium chloride
  • Experimental Validation Results for Diphenyleneiodonium chloride
  • Experimental Validation Results for Diphenyleneiodonium chloride
  • Experimental Validation Results for Diphenyleneiodonium chloride
CAS No.: 4673-26-1
사이즈
가격
재고
수량
Amount: USD 0.00
Please select quantity
or
or

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Diphenyleneiodonium chloride:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • 용액&용해도
  • Protocol
  • 순도&문서
  • References
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Diphenyleneiodonium chloride

More
Customer Validation & Images
Cell Imaging/StainingFlow CytometryWB
  • Cell Imaging/Staining
  • Flow Cytometry
  • Flow Cytometry
  • Flow Cytometry
  • WB

All TRP Channel Isoforms

More

All NADPH Oxidase Isoforms

More

Keywords

MOQ
Minimum order quantity
100 mg

견적 받기 해외재고보유

Other size
견적 받기
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress 로그인
Register
Sign in to MedChemExpress
회원가입

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Diphenyleneiodonium chloride Chemical Structure
    Diphenyleneiodonium chloride Chemical Structure
    1/16
  • 1/16

    Diphenyleneiodonium chloride purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 18;16(1):6621. [Abstract]

    Customer Validation
     Treatment with Diphenyleneiodonium chloride (DPI) inhibited GFP-ATG8a translocation to the tonoplast. The schematic diagram on the left illustrated the timing of DPI addition and the subsequent monensin treatment. Scale bar, 20 μm.

  • 1/16

    Diphenyleneiodonium chloride purchased from MedChemExpress. Usage Cited in: Mar Drugs. 2025 Mar 22;23(4):138. [Abstract]

    Customer Validation
     Effects of diphenyleneiodonium chloride (DPI, 0.1 µM) followed by 48 h treatment with GUA (5 nM) and OLA (3 µM), demonstrated a marked reduction in ROS levels and subsequent cell restoration.

  • 1/16

    Diphenyleneiodonium chloride purchased from MedChemExpress. Usage Cited in: J Transl Med. 2023 Mar 25;21(1):218. [Abstract]

    Customer Validation
     Heated or unheated HCC cells were incubated with or without inhibitors of ROS: NAC (5 mM), MitoTEMPO (500 nM), Diphenyleneiodonium chloride (10 μM), or VAS2870 (10 μM). Apoptosis was quantified using Annexin V-FITC/PI staining and flow cytometry at 24 h after sublethal heat stress.

  • 1/16

    Diphenyleneiodonium chloride purchased from MedChemExpress. Usage Cited in: J Transl Med. 2023 Mar 25;21(1):218. [Abstract]

    Customer Validation
     Heated or unheated HCC cells preincubated with or without inhibitors of NADPH oxidase: Diphenyleneiodonium chloride (10 μM) and VAS2870 (10 μM), MitoSOX fluorescence measured using flow cytometry at 6 h after sublethal heat stress.

  • 1/16

    Diphenyleneiodonium chloride purchased from MedChemExpress. Usage Cited in: Mediators Inflamm. 2020 Jun 6:2020:4321912. [Abstract]

    Customer Validation
     Western blot result shows that compared with the agonist-CD137 group, the phosphorylation level of NF-κB in the DPI group is significantly reduced, indicating the interaction between ROS and NF-κB.

  • Diphenyleneiodonium chloride