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Cat. No.: HY-147971

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Anticancer agent 75

Anticancer agent 75 is a potent anticancer agent. Anticancer agent 75 shows cytotoxicity and selectivity in cancer cell lines. Anticancer agent 75 shows cytotoxicity to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard. Anticancer agent 75 shows good activity of antiplasmodial.

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CAS No.: 2414491-13-5
화학식: C₂₂H₂₄N₂O
분자량:332.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Anticancer agent 75 Chemical Structure

CAS No.: 2414491-13-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
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Calculators
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Bioz

Biological Activity

제품 설명

IC₅₀ & Target< sup>[1]

Plasmodium

Topoisomerase II

All Parasite Isoforms :

All Topoisomerase Isoforms :

In Vitro

Anticancer agent 75 (Compounds 3h) shows good anticancer activity and at least 35 times less toxic than Doxorubicin^[1].
Anticancer agent 75 (Compounds 3h) inhibits cancer cell growth with IC₅₀ values of 333.83 µM, 13.39 µM, 15.31 µM, 15.58 µM, and 4.90 µM for HEK-293, HuCCA-1, A549, HepG2, and MOLT-3, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2414491-13-5
분자량 332.44
화학식 C₂₂H₂₄N₂O
SMILES

CC(C)CCC(C1=C(N2C)C=C(OC)C=C1)=C3C2=NC4=CC=CC=C43
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bhornrawin Akkachairin, et al. Synthesis of Neocryptolepines and Carbocycle-Fused Quinolines and Evaluation of Their Anticancer and Antiplasmodial Activities. Journal Pre-proofs. 2020, 98: 103732. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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Anticancer agent 75

All Parasite Isoforms

All Topoisomerase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Anticancer agent 75 Related Classifications

HY-147971 Related Classifications