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Cat. No.: HY-183534

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CDK2-IN-58

CDK2-IN-58 is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with an IC₅₀ of 0.21 μM. CDK2-IN-58 can be used for cancer research.

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CAS No.: 328061-33-2
화학식: C₁₈H₁₅N₅
분자량:301.35

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK2-IN-58 Chemical Structure

CAS No.: 328061-33-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
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Bioz

Biological Activity

제품 설명

CDK2-IN-58 is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with an IC₅₀ of 0.21 μM. CDK2-IN-58 can be used for cancer research^[1].

IC₅₀ & Target^[1]

CDK2

0.21 μM (IC₅₀)

All CDK Isoforms :

In Vitro

CDK2-IN-58 (Compound 1a) inhibits CDK2-cyclin E enzyme activity with an IC₅₀ of 0.21 μM in a cell-free scintillation proximity assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 328061-33-2
분자량 301.35
화학식 C₁₈H₁₅N₅
SMILES

N1=CC=C(N=C1NC=2C=CC=CC2)C3=C(N=C4C=CC=CN43)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Byth KF, et al. Imidazo[1,2-a]pyridines. Part 2: SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett. 2004 May 3;14(9):2245-8. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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농도 희석 계산기

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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CDK2-IN-58

All CDK Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

CDK2-IN-58 Related Classifications

HY-183534 Related Classifications