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Cat. No.: HY-119800

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Setoperone

Setoperone is an orally active and potent 5-HT₂ receptor antagonist and a moderate dopamine D₂ receptor blocker. Setoperone dissociates from the receptors relatively quickly, but it is easily "captured" by serotonin receptors in the body, resulting in persistent receptor inhibition even after elution. Setoperone can be used to study the negative symptoms of type II schizophrenia and associated mood disorders.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 86487-64-1
화학식: C₂₁H₂₄FN₃O₂S
분자량:401.50

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Setoperone Chemical Structure

CAS No.: 86487-64-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All 5-HT Receptor Isoforms :

All Dopamine Receptor Isoforms :

Chemical Information

CAS No. 86487-64-1
분자량 401.50
화학식 C₂₁H₂₄FN₃O₂S
SMILES

O=C1C(CCN2CCC(CC2)C(C3=CC=C(C=C3)F)=O)=C(N=C4N1CCS4)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ceulemans DL, et al. Effect of serotonin antagonism in schizophrenia: a pilot study with setoperone. Psychopharmacology (Berl). 1985;85(3):329-32.

[2]. Leysen JE, et al. Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone. Psychopharmacology (Berl). 1986;88(4):434-44. [Content Brief]

Calculators

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
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Chemical Information
순도&문서
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Setoperone

All 5-HT Receptor Isoforms

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Setoperone Related Classifications

HY-119800 Related Classifications