LSD1/HDAC6-IN-1
LSD1/HDAC6-IN-1 is an orally active dual inhibitor of lysine specific demethylase 1(LSD1)/Histone deacetylase 6 (HDAC6), with anti-tumor activity. LSD1/HDAC6-IN-1 can be used for the research of multiple myeloma (MM).
For research use only. We do not sell to patients.
- CAS No.: 2738306-38-0
- Formula: C25H33N3O2
- Molecular Weight:407.55
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
|
KDM1/LSD1 |
HDAC6 |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RPMI-8226 | EC50 |
0.28 μM
Compound: 1
|
Antiproliferative activity against human RPMI-8226 cells assessed as reduction in cell viability after 144 hrs
Antiproliferative activity against human RPMI-8226 cells assessed as reduction in cell viability after 144 hrs
|
[PMID: 33359604] |
In Vitro
LSD1/HDAC6-IN-1 shows superior potency in multiple MM lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2738306-38-0
-
Molecular Weight 407.55
-
Formula C25H33N3O2
-
SMILES
ONC(C(C=C1)=CC=C1CCCN(CC2)CCC2CN[C@@H]3[C@@H](C4=CC=CC=C4)C3)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LSD1/HDAC6-IN-1 Related Classifications
HY-131970 Related Classifications
Powered by Bioz