LSD1/HDAC6-IN-1
LSD1/HDAC6-IN-1 is an orally active dual inhibitor of lysine specific demethylase 1(LSD1)/Histone deacetylase 6 (HDAC6), with anti-tumor activity. LSD1/HDAC6-IN-1 can be used for the research of multiple myeloma (MM).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2738306-38-0
- Fòrmula: C25H33N3O2
- Peso molecular:407.55
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
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KDM1/LSD1 |
HDAC6 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RPMI-8226 | EC50 |
0.28 μM
Compound: 1
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Antiproliferative activity against human RPMI-8226 cells assessed as reduction in cell viability after 144 hrs
Antiproliferative activity against human RPMI-8226 cells assessed as reduction in cell viability after 144 hrs
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[PMID: 33359604] |
In Vitro
LSD1/HDAC6-IN-1 shows superior potency in multiple MM lines[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2738306-38-0
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Peso molecular 407.55
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Fòrmula C25H33N3O2
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SMILES
ONC(C(C=C1)=CC=C1CCCN(CC2)CCC2CN[C@@H]3[C@@H](C4=CC=CC=C4)C3)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LSD1/HDAC6-IN-1 Related Classifications
HY-131970 Related Classifications
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