ED11
ED11 is a potent and selective caspase-6 inhibitor with an IC50 of 12.12 nM. ED11 competes with Htt for the caspase-6 active site, and thus reduce Htt cleavage. ED11 can cross the blood-brain barrier (BBB). ED11 has the potential for the study of Huntington's disease (HD).
For research use only. We do not sell to patients.
- CAS No.: 1593480-56-8
- Formula: C116H205N47O37
- Molecular Weight:2850.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Caspase Isoforms
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Biological Activity
Chemical Information
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CAS No. 1593480-56-8
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Molecular Weight 2850.16
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Formula C116H205N47O37
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Sequence
Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln-Ser-Ser-Glu-Ile-Val-Leu-Asp-Gly-Thr-Asp-Asn
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Sequence Shortening
GRKKRRQRRRPPQSSEIVLDGTDN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ED11 Related Classifications
HY-P10822 Related Classifications
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