1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
    5-HT Receptor
  3. Nemonapride

Nemonapride (Synonyms: YM-09151-2; Emilace; Emonapride)

Cat. No.: HY-103415
Handling Instructions

Nemonapride is a highly potent dopamine D2 receptor antagonist with a Ki of 0.06 nM. Nemonapride also activates 5-HT1A receptor with an IC50 of 34 nM. Nemonapride is an antipsychotic that readily passes through the blood brain barrier and exhibits potent neuroleptic effects in animals.

For research use only. We do not sell to patients.

Nemonapride Chemical Structure

Nemonapride Chemical Structure

CAS No. : 75272-39-8

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Description

Nemonapride is a highly potent dopamine D2 receptor antagonist with a Ki of 0.06 nM. Nemonapride also activates 5-HT1A receptor with an IC50 of 34 nM. Nemonapride is an antipsychotic that readily passes through the blood brain barrier and exhibits potent neuroleptic effects in animals[1][2][3].

IC50 & Target

5-HT1A Receptor

34 nM (IC50)

D2 Receptor

0.06 nM (Ki)

Molecular Weight

387.90

Formula

C21H26ClN3O2

CAS No.
SMILES

O=C(N[[email protected]]1[[email protected]@H](C)N(CC2=CC=CC=C2)CC1)C3=CC(Cl)=C(NC)C=C3OC

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Nemonapride
Cat. No.:
HY-103415
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