NT32
NT32 is a selective METTL13 stabilizer with a Kd value of 14 μM. NT32 could occupy both the SAM/SAH-binding pocket and the peptide substrate-binding site of METTL13 simultaneously. NT32 specifically targets and stabilizes METTL13. NT32 shows no inhibitory activity against non-small cell lung cancer.
For research use only. We do not sell to patients.
- Formula: C42H64N18O12S
- Molecular Weight:1045.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Histone Methyltransferase Isoforms
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Biological Activity
Kd: 14 μM (METTL13)[1]
Chemical Information
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Molecular Weight 1045.14
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Formula C42H64N18O12S
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SMILES
O[C@@H]1[C@H](O)[C@@H](CSCC(N=N2)=CN2CC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@](C(N[C@H](C(N)=O)CC3=CNC=N3)=O)([C@H](O)C)[H])=O)CCCCN)=O)CCC(O)=O)=O)CCCCN)=O)O[C@H]1N4C=NC5=C(N)N=CN=C54
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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