1. PI3K/Akt/mTOR
  2. PI3K
  3. PI3K-IN-6

PI3K-IN-6 

Cat. No.: HY-101115
Handling Instructions

PI3K-IN-6 (compound 20a) is an oral active and highly selective phosphoinositide 3-kinase (PI3K) β/δ inhibitor, with IC50 values of 7.8 nM/5.3 nM for PI3K β/δ, respectively. PI3K-IN-6 (compound 20a) has potential top treat phosphatase and tensin homolog (PTEN) feficient tumors.

For research use only. We do not sell to patients.

PI3K-IN-6 Chemical Structure

PI3K-IN-6 Chemical Structure

CAS No. : 1842380-77-1

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Description

PI3K-IN-6 (compound 20a) is an oral active and highly selective phosphoinositide 3-kinase (PI3K) β/δ inhibitor, with IC50 values of 7.8 nM/5.3 nM for PI3K β/δ, respectively. PI3K-IN-6 (compound 20a) has potential top treat phosphatase and tensin homolog (PTEN) feficient tumors[1].

IC50 & Target[1]

PI3Kβ

7.8 nM (IC50)

PI3Kδ

5.3 nM (IC50)

PI3Kα

850 nM (IC50)

Molecular Weight

450.26

Formula

C₁₇H₁₄Cl₂FN₉O

CAS No.

1842380-77-1

SMILES

FC1=CC(Cl)=C(N=C([[email protected]@H](NC2=C(Cl)C(N)=NC(N)=N2)C)N(C3=NNC=C3)C4=O)C4=C1

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Room temperature in continental US; may vary elsewhere

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Please store the product under the recommended conditions in the Certificate of Analysis.

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PI3K-IN-6
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