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Cat. No.: HY-168319

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PI3Kγ ligand 1

PI3Kγ ligand 1 is a Ligand for Target Protein for PROTAC (HY-137340) .

For research use only. We do not sell to patients.

CAS No.: 2769753-45-7
Formula: C₂₆H₂₉N₅O₃S
Molecular Weight:491.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

PI3Kγ ligand 1 Chemical Structure

CAS No.: 2769753-45-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

PI3Kγ ligand 1 is a Ligand for Target Protein for PROTAC (HY-137340) ^[1].

IC₅₀ & Target^[1]

PI3Kγ

All PI3K Isoforms :

Chemical Information

CAS No. 2769753-45-7
Molecular Weight 491.61
Formula C₂₆H₂₉N₅O₃S
SMILES

NCCCN(C1CC1)S(C2=CC=C(C3=CN=C(N)C(C4=CC(CCNC5=O)=C5C=C4)=C3)C=C2)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Donovan KA, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020;183(6):1714-1731.e10. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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