2. Epigenetics
  3. Histone Methyltransferase
  4. PRMT7-IN-1

PRMT7-IN-1 (Compound 14) is a PRMT7 inhibitor with an IC50 of 2.1 μM. PRMT7-IN-1 shows anticancer activity against different cancer cells.

For research use only. We do not sell to patients.

PRMT7-IN-1 Chemical Structure

PRMT7-IN-1 Chemical Structure

CAS No. : 2247753-73-5

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PRMT7-IN-1 Related Antibodies

Top Publications Citing Use of Products

View All Histone Methyltransferase Isoform Specific Products:

View All Isoforms
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

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Description

PRMT7-IN-1 (Compound 14) is a PRMT7 inhibitor with an IC50 of 2.1 μM. PRMT7-IN-1 shows anticancer activity against different cancer cells[1].

In Vitro

PRMT7-IN-1 (Compound 14) shows antitumor activity with IC50 values of 2.250, 1.267, 4.4, 1 and 3.342 μM against ES-2, A2780S, Jeko-1, HO8910 and A2780/T cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

PRMT7-IN-1 Related Antibodies
Molecular Weight

435.45

Formula

C23H22FN5O3
CAS No.
SMILES

NC1=CC(C)=NC2=CC=C(NC3=NC(C4=CC(OC)=C(OC)C(OC)=C4)=NC=C3F)C=C12
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PRMT7-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PRMT7-IN-12247753-73-5Histone Methyltransferaselung canceroophoromaprostate cancerPC-9Calu-1NCI-H1975NCI-H358H2228Inhibitorinhibitorinhibit

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