1. Epigenetics
    PROTAC
  2. Epigenetic Reader Domain
    Ligand for Target Protein for PROTAC
  3. PROTAC BRD4-binding moiety 1

PROTAC BRD4-binding moiety 1 

Cat. No.: HY-107442
Handling Instructions

PROTAC BRD4-binding moiety 1 is a ligand for BRD4. PROTAC BRD4-binding moiety 1 binds to cereblon ligand via a linker to form PROTAC to degrade BRD4 (HY-133136).

For research use only. We do not sell to patients.

PROTAC BRD4-binding moiety 1 Chemical Structure

PROTAC BRD4-binding moiety 1 Chemical Structure

CAS No. : 2101200-10-4

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Description

PROTAC BRD4-binding moiety 1 is a ligand for BRD4. PROTAC BRD4-binding moiety 1 binds to cereblon ligand via a linker to form PROTAC to degrade BRD4 (HY-133136)[1].

IC50 & Target[1]

BRD4

 

In Vitro

PROTAC BRD4 Degrader-2 is an efficacious PROTAC BRD4 degrader with an IC50 of 14.2 nM against BRD4 BD1[1].

Molecular Weight

371.43

Formula

C₂₃H₂₁N₃O₂

CAS No.

2101200-10-4

SMILES

O=C1N(C)C2=C(C=C(C3=C(C)ON=C3C)C=C2)C(C4=CC=CC=C4)N1CC#C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

PROTAC BRD4-binding moiety 1Epigenetic Reader DomainLigand for Target Protein for PROTACTarget Protein-binding MoietyInhibitorinhibitorinhibit

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PROTAC BRD4-binding moiety 1
Cat. No.:
HY-107442
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