Relitegatide TFA
Based on 1 Customer Validation
Relitegatide TFA is a selective αvβ6 integrin-binding peptide. Relitegatide TFA functions as the αvβ6-binding building block of the trimeric PET probe Trivehexin. Relitegatide TFA can be used for research on pancreatic ductal adenocarcinoma (PDAC).
For research use only. We do not sell to patients.
- Formula: C51H75N13O13·xC2HF3O2
- Molecular Weight:1078.22 (free base)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
αvβ6 |
RDC Peptide |
Chemical Information
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Molecular Weight 1078.22 (free base)
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Formula C51H75N13O13·xC2HF3O2
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SMILES
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N2[C@H](CCC2)C(N(C)[C@@H](CCCCN)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@H]4CC(C)C)=O)=O)=O)=O)=O)=O)=O)[C@H](C)NC4=O.OC(C(F)(F)F)=O.[x]
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Sequence
c[Tyr-Arg-Gly-Asp-Leu-Ala-Tyr-DPro-(NMe)Lys]
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Sequence Shortening
c[YRGDLAYp(NMe)K]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
References
[1]. Quigley NG, et al. PET/CT imaging of head-and-neck and pancreatic cancer in humans by targeting the "Cancer Integrin" αvβ6 with Ga-68-Trivehexin. Eur J Nucl Med Mol Imaging. 2022;49(4):1136-1147. [Content Brief]
[2]. Zhang X, et al. Design, Synthesis, and Biological Evaluation of [18F]AlF-Labeled Integrin αvβ6-Targeting Tracers for Pancreatic Cancer Imaging. J Med Chem. 2025 Jul 10;68(13):14028-14040. [Content Brief]
Relitegatide TFA Related Classifications
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