Revamilast
Revamilast (GRC 4039) is an orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 3 nM. Revamilast inhibits the production of TNF-α. It can be used for research on rheumatoid arthritis, plaque psoriasis, asthma, and other inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 893555-90-3
- Formula: C18H9Cl2F2N3O4
- Molecular Weight:440.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PDE4 3 nM (IC50) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 893555-90-3
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Molecular Weight 440.18
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Formula C18H9Cl2F2N3O4
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SMILES
O=C(C1=C(C2=C3C=CN=C2)C(O3)=C(OC(F)F)C=C1)NC4=C(Cl)C=[N+]([O-])C=C4Cl
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Synonyms
GRC 4039
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)