RS-104966
Based on 1 Customer Validation
RS-104966 is a potent collagenase-1 (MMP-1) inhibitor. RS-104966 induces a conformational change in the side chains of the S10 pocket of MMP-1.
For research use only. We do not sell to patients.
- Purity: 98.39%
- CAS No.: 193022-38-7
- Formula: C19H21NO6S
- Molecular Weight:391.44
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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collagenases 1 |
Chemical Information
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CAS No. 193022-38-7
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Appearance Solid
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Molecular Weight 391.44
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Formula C19H21NO6S
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Color White to off-white
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SMILES
O=C(NO)CC1(S(=O)(C2=CC=C(OC3=CC=CC=C3)C=C2)=O)CCOCC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (255.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5547 mL | 12.7733 mL | 25.5467 mL | 63.8667 mL |
| 5 mM | 0.5109 mL | 2.5547 mL | 5.1093 mL | 12.7733 mL | |
| 10 mM | 0.2555 mL | 1.2773 mL | 2.5547 mL | 6.3867 mL | |
| 15 mM | 0.1703 mL | 0.8516 mL | 1.7031 mL | 4.2578 mL | |
| 20 mM | 0.1277 mL | 0.6387 mL | 1.2773 mL | 3.1933 mL | |
| 25 mM | 0.1022 mL | 0.5109 mL | 1.0219 mL | 2.5547 mL | |
| 30 mM | 0.0852 mL | 0.4258 mL | 0.8516 mL | 2.1289 mL | |
| 40 mM | 0.0639 mL | 0.3193 mL | 0.6387 mL | 1.5967 mL | |
| 50 mM | 0.0511 mL | 0.2555 mL | 0.5109 mL | 1.2773 mL | |
| 60 mM | 0.0426 mL | 0.2129 mL | 0.4258 mL | 1.0644 mL | |
| 80 mM | 0.0319 mL | 0.1597 mL | 0.3193 mL | 0.7983 mL | |
| 100 mM | 0.0255 mL | 0.1277 mL | 0.2555 mL | 0.6387 mL |