2. Epigenetics TGF-beta/Smad
  3. PKC
  4. SAMβA

SAMβA is conjugated to the cell permeable peptide TAT47-57. SAMβA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAMβA is a selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats.

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Custom Peptide Synthesis

SAMβA

SAMβA Chemical Structure

CAS No. : 2429946-75-6

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Based on 1 publication(s) in Google Scholar

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SAMβA Related Antibodies

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Description

SAMβA is conjugated to the cell permeable peptide TAT47-57. SAMβA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAMβA is a selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats[1].

Molecular Weight

1168.22

Formula

C50H73N17O16
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

RNAENFDRF
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (85.60 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8560 mL 4.2800 mL 8.5600 mL
5 mM 0.1712 mL 0.8560 mL 1.7120 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

Animal weight
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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.8560 mL 4.2800 mL 8.5600 mL 21.4001 mL
5 mM 0.1712 mL 0.8560 mL 1.7120 mL 4.2800 mL
10 mM 0.0856 mL 0.4280 mL 0.8560 mL 2.1400 mL
15 mM 0.0571 mL 0.2853 mL 0.5707 mL 1.4267 mL
20 mM 0.0428 mL 0.2140 mL 0.4280 mL 1.0700 mL
25 mM 0.0342 mL 0.1712 mL 0.3424 mL 0.8560 mL
30 mM 0.0285 mL 0.1427 mL 0.2853 mL 0.7133 mL
40 mM 0.0214 mL 0.1070 mL 0.2140 mL 0.5350 mL
50 mM 0.0171 mL 0.0856 mL 0.1712 mL 0.4280 mL
60 mM 0.0143 mL 0.0713 mL 0.1427 mL 0.3567 mL
80 mM 0.0107 mL 0.0535 mL 0.1070 mL 0.2675 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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SAMβA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAMβA2429946-75-6PKCProtein kinase Ccell permeable peptide TAT47-57inhibitory peptide SAMβAMfn1-βIIPKC associationheart failureInhibitorinhibitorinhibit

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