10114 Results for "

biolipid function

" in MedChemExpress (MCE) Product Catalog:
Products (10114)

10114 Results for "biolipid function" in MCE Product Catalog:

42
42 Cited Publications
Cat. No.: HY-D0989
CAS No.: 145037-81-6
Rhod-2 is a high-affinity visible light excitation wavelength Ca 2+ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .
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35
35 Cited Publications
Cat. No.: HY-F0004
CAS No.: 1094-61-7
Synonyms: β-Nicotinamide mononucleotide; β-NM; NMN
Fosribnicotinamide (β-nicotinamide mononucleotide) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD + intermediate. The pharmacological activities of Fosribnicotinamide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity .
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34
34 Cited Publications
Cat. No.: HY-50910
CAS No.: 162635-04-3
Synonyms: CCI-779
Temsirolimus is an inhibitor of mTOR with an IC50 of 1.76 μM. Temsirolimus activates autophagy and prevents deterioration of cardiac function in animal model .
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33
33 Cited Publications
Cat. No.: HY-101086
CAS No.: 2260-50-6
Purity:  98.59%
Synonyms: ACh iodide
Acetylcholine iodide is a muscarinic receptor modulator. Acetylcholine iodide specifically binds to muscarinic receptors, inhibits sodium absorption, and induces chloride secretion. Acetylcholine iodide changes intestinal ion transport, enhances intestinal secretory function, induces or maintains mammary gland development and lactation. Acetylcholine iodide can be used for intestinal ion transport regulation and mammary gland physiological function research .
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33
33 Cited Publications
Cat. No.: HY-B0282A
CAS No.: 66-23-9
Synonyms: ACh bromide
Acetylcholine bromide is an organic choline salt compound commonly used in neurophysiology and pharmacology experiments. It plays an important role in the nervous system, acting as a neurotransmitter that transmits signals and regulates many important physiological functions. Due to its special biological activity, Acetylcholine bromide is widely used in the study of neurotransmitters, nerve damage and muscle movement.
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33
33 Cited Publications
Cat. No.: HY-14252A
CAS No.: 100286-97-3
Synonyms: Win 47203 lactate
Research Areas:  

Cardiovascular Disease

Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock .
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33
33 Cited Publications
Cat. No.: HY-D0836
CAS No.: 25102-12-9
Synonyms: Ethylenediaminetetraacetic acid dipotassium dihydrate
EDTA dipotassium dihydrate is a metal ion chelator that forms stable and water-soluble chelates with a variety of metal ions. EDTA dipotassium is commonly used as a blood anticoagulant, which can effectively prevent blood coagulation and maintain the morphology and function of cells in blood samples. In the industrial field, EDTA dipotassium can be used to remove the adverse effects of metal ions and prevent oxidation and deterioration caused by metal ions .
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32
32 Cited Publications
Cat. No.: HY-19356
CAS No.: 84573-16-0
Synonyms: Roc-A
Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia .
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30
30 Cited Publications
Cat. No.: HY-17571A
CAS No.: 6233-83-6
Synonyms: α-Hypophamine acetate; Oxytocic hormone acetate
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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30
30 Cited Publications
Cat. No.: HY-17571
CAS No.: 50-56-6
Synonyms: α-Hypophamine; Oxytocic hormone
Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .
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29
29 Cited Publications
Cat. No.: HY-101903
CAS No.: 300657-03-8
Purity:  99.93%
Target:  

FABP

BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .
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29
29 Cited Publications
Cat. No.: HY-101903A
CAS No.: 2802523-05-1
Purity:  99.93%
Target:  

FABP

BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells .
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28
28 Cited Publications
Cat. No.: HY-12512
CAS No.: 849214-04-6
Purity:  98.28%
Synonyms: Cyclic GMP-AMP; 3',3'-cGAMP
Target:  

STING

Research Areas:  

Inflammation/Immunology

cGAMP (Cyclic GMP-AMP) functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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28
28 Cited Publications
Cat. No.: HY-N0729
CAS No.: 60-33-3
Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
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28
28 Cited Publications
Cat. No.: HY-110385
CAS No.: 2407516-83-8
Purity:  98.47%
Synonyms: Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium
cGAMP (Cyclic GMP-AMP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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28
28 Cited Publications
Cat. No.: HY-110385A
Purity:  95.19%
Synonyms: Cyclic GMP-AMP diammonium; 3',3'-cGAMP diammonium
cGAMP (Cyclic GMP-AMP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .
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22
22 Cited Publications
Cat. No.: HY-141644
CAS No.: 2765218-56-0
Purity:  99.10%
Target:  

Annexin A YAP

Research Areas:  

Inflammation/Immunology

PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 µM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity .
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22
22 Cited Publications
Cat. No.: HY-P1439
CAS No.: 1449566-36-2
Research Areas:  

Inflammation/Immunology

RS 09 is an LPS (HY-D1056) peptide mimic and TLR4 agonist. RS 09 can bind to TLR-4 and activate NF-κB. RS 09 can function as an adjuvant in vivo, enhancing the antigen-specific immune response .
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22
22 Cited Publications
Cat. No.: HY-P1439A
Research Areas:  

Inflammation/Immunology

RS 09 TFA is an LPS (HY-D1056) peptide mimic and TLR4 agonist. RS 09 TFA can bind to TLR-4 and activate NF-κB. RS 09 TFA can function as an adjuvant in vivo, enhancing the antigen-specific immune response .
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22
22 Cited Publications
Cat. No.: HY-117383
CAS No.: 790702-57-7
Purity:  99.97%
Synonyms: ML414
Target:  

Virus Protease

Research Areas:  

Cancer

NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B . NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability .
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