407 Results for "

indole ester

" in MedChemExpress (MCE) Product Catalog:
Products (407)

407 Results for "indole ester" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-18569S
CAS No.: 76937-78-5
Synonyms: indole-3-acetic acid-d5; 3-IAA-d5
3-Indoleacetic acid-d5 (Indole-3-acetic acid-d5) is the deuterated-labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
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2 Cited Publications
Cat. No.: HY-B2132
CAS No.: 61-54-1
Synonyms: 3-(2-Aminoethyl)indole~2-(3-Indolyl)ethylamine
Tryptamine is a selective, blood-brain-penetrating 5-HT4 receptor agonist (EC50=1-3 mM) and an endogenous ligand of the aryl hydrocarbon receptor (AHR) (Kd=10-50 nM). Tryptamine promotes intestinal anion secretion and fluid transport by activating G protein-coupled receptors (GPCRs) and accelerates gastrointestinal motility. Tryptamine regulates Th17/Treg balance to inhibit neuroinflammation, competitively binds to 5-HT receptors to regulate central nervous system activity, and participates in temperature regulation and spinal reflex regulation as a neuromodulator. Tryptamine can be used to study intestinal motility disorders such as functional constipation, and has shown significant efficacy in multiple sclerosis models .
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2 Cited Publications
Cat. No.: HY-N2197
CAS No.: 35467-43-7
Hirsuteine is an indole alkaloid extracted from Uncaria rhynchophylla. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes .
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2 Cited Publications
Cat. No.: HY-136199
CAS No.: 352554-02-0
Purity:  98.15%
Target:  

Sirtuin CMV

Research Areas:  

Infection

SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM . SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity .
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2 Cited Publications
Cat. No.: HY-N2179
CAS No.: 487-58-1
Hypaphorine is an indole found in Caragana korshinskii. Hypaphorine has neurological and glucose-lowering effects. Hypaphorine prevents Lipopolysaccharides (LPS) (HY-D1056)-mediated acute lung injury (ALI) and proinflammatory response via inactivating the p38/JNK signaling pathway by upregulating DUSP1 .
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2 Cited Publications
Cat. No.: HY-W014971
CAS No.: 343-94-2
Tryptamine hydrochloride belongs to the class of indole alkaloids and is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds. It can also occur naturally in certain plants and animals, including fungi and mammals. Due to the psychoactive properties of Tryptamine hydrochloride and its derivatives, its use and possession are controlled substances in many countries.
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2 Cited Publications
Cat. No.: HY-Y0136
CAS No.: 771-51-7
3-Indoleacetonitrile is an indole derivative with anti-influenza activity. 3-Indoleacetonitrile is a plant hormone produced by cruxiferous vegetables. 3-Indoleacetonitrile exerts profound antiviral activity against a broad spectrum of influenza A viruses, HSV-1 and VSV viruses in vitro. 3-Indoleacetonitrile diminishes lung virus titers and alleviates lung lesions in vivo. 3-Indoleacetonitrile induces an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile can be used in research for combating viral infections including COVID-19, HSV-1, and VSV .
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2 Cited Publications
Cat. No.: HY-111334
CAS No.: 105748-59-2
Purity:  99.74%
Synonyms: Brassinine
Brassinin is an indole derivative found in cruciferous plants. Brassinin acts as an IDO inhibitor (Ki = 97.7 μM). Brassinin inhibits angiogenesis and induces apoptosis, autophagy, paraptosis, ROS production, and ER stress. Brassinin selectively stimulates lysosomal degradation of Tie2 and promotes lysosomal and proteasomal degradation of FGFR1 in endothelial cells, downregulating AKT and ERK phosphorylation. Brassinin inhibits endothelial cell proliferation, migration, tube formation, spheroid sprouting, and angiogenesis. Brassinin inhibits PI3K/Akt/mTOR/S6K1 signaling, upregulates p21 and p27, and induces G1 phase cell cycle arrest through RB hypophosphorylation. Brassinin inhibits tyrosinase catalytic activity, reduces tyrosinase mRNA, and inhibits MITF nuclear translocation. Brassinin is used for research on triple-negative breast cancer, chronic myeloid leukemia, colon cancer, glioma, atherosclerosis, and skin cancer .
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1
1 Cited Publications
Cat. No.: HY-N0186
CAS No.: 133-32-4
Synonyms: indolebutyric acid
Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
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1 Cited Publications
Cat. No.: HY-N0186A
CAS No.: 60096-23-3
Synonyms: indolebutyric acid potassium
Target:  

Endogenous Metabolite

Research Areas:  

Others

Indole-3-butyric acid (Indolebutyric acid) potassium is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid potassium is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
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1 Cited Publications
Cat. No.: HY-W015420
CAS No.: 1670-82-2
1H-Indole-6-carboxylic acid is an allosteric binder of HIV-1 protease. 1H-Indole-6-carboxylic acid can be used in studies related to HIV-1 infection .
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1 Cited Publications
Cat. No.: HY-W002128
CAS No.: 16732-70-0
Ethyl 5-bromo-1H-indole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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1 Cited Publications
Cat. No.: HY-W012361
CAS No.: 17826-04-9
Synonyms: 6-Bromoindole-3-carboxaldehyde
6-Bromo-1H-indole-3-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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1
1 Cited Publications
Cat. No.: HY-W016393
CAS No.: 2305-13-7
Dihydroconiferyl alcohol is a cell division factor. Dihydroconiferyl alcohol can be isolated from the American sycamore (Acer pseudoplatanus L.). Dihydroconiferyl alcohol inhibits the degradation of Indole-3-acetic acid (HY-18569). Dihydroconiferyl alcohol can stimulate the growth of soybean and tobacco callus tissue and synergistically enhance Indole-3-acetic acid-induced hypocotyl elongation in cucumber. Dihydroconiferyl alcohol can be used in the research of plant growth regulation .
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1 Cited Publications
Cat. No.: HY-A0220
CAS No.: 24815-24-5
Synonyms: Reserpinine
Rescinnamine is a derivative of the indole alkaloid reserpine. Rescinnamine shows sedative effects. Rescinnamine can be used for hypertension research .
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1 Cited Publications
Cat. No.: HY-32813
CAS No.: 104830-06-0
Synonyms: 3-Iodopyridin-2-amine
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts things. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, a potential obstacle for future synthesis .
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1 Cited Publications
Cat. No.: HY-N2193
CAS No.: 7729-23-9
Hirsutine, an indole alkaloid of Uncaria rhynchophylla, exhibits anti-cancer activity. Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity .
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1 Cited Publications
Cat. No.: HY-111208
CAS No.: 883098-58-6
Purity:  99.71%
Target:  

Phospholipase

Research Areas:  

Cancer

CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. CCT129957 inhibits Ca 2+ release in squamous carcinoma cells at ~15 μM .
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1 Cited Publications
Cat. No.: HY-P2876
CAS No.: 9024-00-4
Target:  

Bacterial

Research Areas:  

Others

Tryptophanase is a zymogen-converting enzyme and inducible enzyme that can convert its inactive precursor form into an active enzyme without additional polypeptide synthesis. In Escherichia coli K12, tryptophanase functions as an inducible enzyme, and its induction kinetics are similar to those of β-galactosidase. Tryptophanase catalyzes the conversion of L-tryptophan to indole .
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1 Cited Publications
Cat. No.: HY-20897A
CAS No.: 25197-99-3
5-Bromo-L-tryptophan is a substrate of PLP-dependent enzyme AetE, as well as an indole alkaloid and Amino acid derivative. 5-Bromo-L-tryptophan can be isolated from Semenospongia sp. 5-Bromo-L-tryptophan can be converted into 5-bromoindole (HY-30236) via AetE-mediated catalysis. 5-Bromo-L-tryptophan is applicable to colon cancer research .
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